Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498747 | 0.88 | AADAT (0.43) | AADATP2RY14SMN1; SMN2ALDH1A1NR4A2 | |
| SCHEMBL12498769 | 0.87 | GPR52 (0.44) | AADATSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12499380 | 0.85 | AADAT (0.41) | AADATP2RY14PTGER1NR4A2GFER | |
| SCHEMBL12498729 | 0.85 | SRD5A2 (0.46) | AADATP2RY14ALDH1A1POLB | |
| SCHEMBL12499848 | 0.84 | AADAT (0.41) | AADATP2RY14SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL12499272 | 0.81 | HCAR2 (0.45) | P2RY14SMN1; SMN2POLB | |
| SCHEMBL12499717 | 0.79 | KDM4E (0.46) | SMN1; SMN2ALDH1A1NPSR1POLB | |
| SCHEMBL12499319 | 0.76 | KDM4E (0.43) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL12499265 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL12499705 | 0.75 | HCAR2 (0.42) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |