Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499400 | 0.86 | VDR (0.49) | SMN1; SMN2LMNAPOLB | |
| SCHEMBL12498729 | 0.85 | SRD5A2 (0.46) | LMNAEGLN1ALDH1A1POLBPTGDR2 | |
| SCHEMBL12498677 | 0.85 | PLA2G2A (0.45) | SMN1; SMN2LMNAEGLN1USP2CYP1A2 | |
| SCHEMBL12499850 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1P2RX3 | |
| SCHEMBL12499672 | 0.80 | RNASEH1 (0.43) | LMNAPOLBPTGDR2 | |
| SCHEMBL12499272 | 0.76 | HCAR2 (0.45) | SMN1; SMN2LMNAPOLBP2RX3 | |
| SCHEMBL12499305 | 0.76 | AADAT (0.43) | SMN1; SMN2CYP1A2CYP2C19ALDH1A1POLB | |
| SCHEMBL3718927 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2LMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL12499862 | 0.71 | PLA2G2A (0.45) | SMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL12499736 | 0.71 | SRD5A2 (0.46) | LMNAPOLBPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |