Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498726 | 0.86 | HSP90AA1 (0.47) | ADCY10KMT2AMEN1PKMRAB9A | |
| SCHEMBL12499400 | 0.84 | VDR (0.49) | POLBKMT2AMEN1RAB9AMAPT | |
| SCHEMBL12499672 | 0.83 | RNASEH1 (0.43) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL12499705 | 0.83 | HCAR2 (0.42) | HCAR2KMT2AMEN1PKMRAB9A | |
| SCHEMBL12498775 | 0.83 | HCAR2 (0.42) | HCAR2KMT2AMEN1PKMRAB9A | |
| SCHEMBL12499305 | 0.81 | AADAT (0.43) | POLBSMN1; SMN2P2RY14 | |
| SCHEMBL12499265 | 0.76 | SMN1; SMN2 (0.40) | POLBSMN1; SMN2LMNAP2RX3 | |
| SCHEMBL18148761 | 0.75 | MEN1 (0.49) | KMT2AMEN1PKMLMNA | |
| SCHEMBL12499891 | 0.74 | KMT2A (0.51) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL12498729 | 0.73 | SRD5A2 (0.46) | POLBLMNAP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |