Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12498747 | 0.87 | AADAT (0.43) | RAB9AKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL12499891 | 0.86 | KMT2A (0.51) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL12499378 | 0.85 | MAPT (0.40) | RAB9AKMT2AMAPTMEN1ADRA1A | |
| SCHEMBL12499826 | 0.85 | CCR2 (0.39) | TRPV1 | |
| SCHEMBL12499272 | 0.83 | HCAR2 (0.45) | HCAR2RAB9ACSNK2A2CSNK2BKMT2A | |
| SCHEMBL12498775 | 0.81 | HCAR2 (0.42) | HCAR2RAB9ACSNK2A2CSNK2BKMT2A | |
| SCHEMBL12499736 | 0.79 | SRD5A2 (0.46) | KMT2AMEN1KDM4CLMNA | |
| SCHEMBL12499305 | 0.75 | AADAT (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12499717 | 0.73 | KDM4E (0.46) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL12498726 | 0.73 | HSP90AA1 (0.47) | RAB9AKMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |