Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499499 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NLRP3TSHRKMT2AIDO1 | |
| SCHEMBL17857571 | 1.00 | ALDH1A1 (0.44) | ALDH1A1NLRP3TSHRKMT2AIDO1 | |
| Hydrochloric Acid SCHEMBL8618217 | 0.98 | IDO1 (0.44) | ALDH1A1NLRP3TSHRKMT2AIDO1 | |
| SCHEMBL5720819 | 0.90 | ALDH1A1 (0.41) | ALDH1A1NLRP3TSHRKMT2AIDO1 | |
| SCHEMBL5720874 | 0.87 | TSHR (0.44) | ALDH1A1TSHRKMT2ACYP1A2CYP2C19 | |
| SCHEMBL29219877 | 0.85 | MAPT (0.45) | ALDH1A1NLRP3TSHRKMT2AMAPT | |
| SCHEMBL3224732 | 0.84 | NLRP3 (0.44) | ALDH1A1NLRP3TSHRKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL381611 | 0.84 | MEN1 (0.43) | ALDH1A1KMT2AIDO1TDO2MAPT | |
| Hydrochloric Acid SCHEMBL4599230 | 0.84 | MEN1 (0.43) | ALDH1A1KMT2AIDO1TDO2MAPT | |
| SCHEMBL2320013 | 0.84 | ALDH1A1 (0.47) | ALDH1A1NLRP3TSHRKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106834081-A | A kind of vertical purple potato pears compound fruit vinegar fermentation tank control system and its method of work | 徐州工程学院 | 2017-06-13 | — | — | CN | claimed |
| EP-3353163-B1 | 2,3,4,5-TETRAHYDROPYRIDIN-6-AMINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-05 | — | — | EP | disclosed |
| CN-106834081-A | A kind of vertical purple potato pears compound fruit vinegar fermentation tank control system and its method of work | 徐州工程学院 | 2017-06-13 | — | — | CN | disclosed |
| WO-2017050978-A1 | 2,3,4,5-TETRAHYDROPYRIDIN-6-AMINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-30 | — | — | WO | disclosed |
| US-9120783-B2 | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-09-01 | — | — | US | disclosed |
| US-9029559-B2 | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2015-05-12 | — | — | US | disclosed |
| US-20140194445-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-07-10 | — | — | US | disclosed |
| US-20140135328-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-05-15 | — | — | US | disclosed |
| US-8669370-B2 | Substituted 3-heteroaroylamino-propionic acid derivatives and their use as pharmaceuticals | SANOFI (FR) | 2014-03-11 | — | — | US | disclosed |
| EP-2667870-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2013-12-04 | — | — | EP | disclosed |
| US-20120252809-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-10-04 | — | — | US | disclosed |
| WO-2012101197-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135328-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSL, CTSF, CTSV | ALDH1A1 829/4885NLRP3 956/4885TSHR 2933/4885 |
| US-20120252809-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSL, CTSF, CTSV | ALDH1A1 829/4885NLRP3 956/4885TSHR 2933/4885 |
| US-20140194445-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSL, CTSF, CTSV | ALDH1A1 829/4885NLRP3 956/4885TSHR 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.