Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770989 | 0.88 | NLRP3 (0.46) | NLRP3ALDH1A1TSHRKMT2ACES2 | |
| SCHEMBL12499499 | 0.84 | ALDH1A1 (0.44) | NLRP3ALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL17857571 | 0.84 | ALDH1A1 (0.44) | NLRP3ALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL12499503 | 0.84 | ALDH1A1 (0.44) | NLRP3ALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL28032089 | 0.84 | MEN1 (0.44) | ALDH1A1KMT2ACES2CES1CYP3A4 | |
| SCHEMBL10249906 | 0.84 | TSHR (0.47) | NLRP3ALDH1A1TSHRKMT2ACASP1 | |
| SCHEMBL8770892 | 0.84 | MEN1 (0.44) | ALDH1A1KMT2ACES2CES1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8618217 | 0.83 | IDO1 (0.44) | NLRP3ALDH1A1TSHRKMT2ACYP3A4 | |
| SCHEMBL16797693 | 0.83 | CA12 (0.46) | NLRP3ALDH1A1TSHRKMT2ACASP1 | |
| SCHEMBL18726494 | 0.82 | NLRP3 (0.46) | NLRP3ALDH1A1TSHRKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069683-A1 | Organic metal compound and process for preparing optically-active alcohols using the same | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20090062573-A1 | Organic metal compound and process for preparing optically-active alcohols using the same | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-0451668-B1 | Process for the production of optically active alkyl 3-aryl-3-hydroxypropionates | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5202457-A | Enzyme catalyzed transesterification, resolution of optical active alkyl 3-aryl-3-hydroxypropionate | CHISSO CORPORATION (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0451668-A2 | Optically active alkyl 3-aryl-3-hydroxypropionates and a method for producing thereof | CHISSO CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062573-A1 | Organic metal compound and process for preparing optically-active alcohols using the same | ADH1C, ADH1A, ADH5 | NLRP3 4463/4885ALDH1A1 26/4885TSHR 1544/4885 |
| US-20100069683-A1 | Organic metal compound and process for preparing optically-active alcohols using the same | ADH1C, ADH1A, ADH5 | NLRP3 4463/4885ALDH1A1 26/4885TSHR 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.