Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | GRM5 | P41594 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527356 | 0.83 | RAB9A (0.69) | FKBP1ASMN1; SMN2HPGDALDH1A1RAB9A | |
| SCHEMBL9529304 | 0.83 | RAB9A (0.97) | FKBP1ASMN1; SMN2HPGDALDH1A1RAB9A | |
| SCHEMBL16679281 | 0.83 | RAB9A (0.69) | FKBP1ASMN1; SMN2HPGDGRM5ALDH1A1 | |
| SCHEMBL9528422 | 0.83 | SMN1; SMN2 (0.97) | FKBP1ASMN1; SMN2HPGDALDH1A1RAB9A | |
| SCHEMBL11083864 | 0.83 | FKBP1A (0.68) | FKBP1ASMN1; SMN2HPGDGRM5ALDH1A1 | |
| SCHEMBL9564044 | 0.79 | SMN1; SMN2 (0.51) | FKBP1ASMN1; SMN2HPGDGRM5ALDH1A1 | |
| SCHEMBL1540452 | 0.77 | SMN1; SMN2 (0.57) | FKBP1ASMN1; SMN2HPGDGRM5ALDH1A1 | |
| SCHEMBL1540451 | 0.77 | SMN1; SMN2 (0.57) | FKBP1ASMN1; SMN2HPGDGRM5ALDH1A1 | |
| SCHEMBL20988787 | 0.77 | KMT2A (0.57) | FKBP1ASMN1; SMN2HPGDALDH1A1RAB9A | |
| SCHEMBL18043568 | 0.76 | ALDH1A1 (0.71) | FKBP1ASMN1; SMN2HPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343069-A1 | Heterocyclic aspartyl protease inhibitors | Schering Corporation (US) | 2011-07-13 | — | — | EP | disclosed |