Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503286 | 0.79 | FKBP1A (0.71) | SMN1; SMN2RAB9ANPC1ALDH1A1GRM5 | |
| SCHEMBL9871967 | 0.73 | FAAH (0.57) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL1930719 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3074561 | 0.71 | FFAR1 (0.60) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL11272257 | 0.71 | KMT2A (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL9528419 | 0.70 | NPC1 (0.62) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL10958177 | 0.70 | HPGD (0.48) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL9528422 | 0.70 | SMN1; SMN2 (0.97) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3920722 | 0.70 | ALDH1A1 (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL1932674 | 0.67 | FFAR1 (0.56) | SMN1; SMN2RAB9ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |