Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 14/20 | 0.34 |
| ▸ | CNR1 | P21554 | 7/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20970146 | 0.90 | SIGMAR1 (0.32) | MEN1KMT2ANPSR1CNR2CNR1 | |
| SCHEMBL16387011 | 0.82 | — | — | |
| SCHEMBL2828857 | 0.80 | P2RX7 (0.35) | MEN1KMT2ASIGMAR1OPRK1 | |
| SCHEMBL3000133 | 0.79 | SIGMAR1 (0.33) | MEN1KMT2ANPSR1ALDH1A1POLB | |
| SCHEMBL17883720 | 0.79 | CNR2 (0.36) | ALDH1A1POLBMAPTCNR2CNR1 | |
| SCHEMBL3005852 | 0.77 | MEN1 (0.38) | MEN1KMT2ANPSR1ALDH1A1POLB | |
| SCHEMBL29033698 | 0.76 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1OPRK1 | |
| SCHEMBL1735054 | 0.75 | P2RX7 (0.32) | MEN1KMT2AOPRK1 | |
| SCHEMBL27762631 | 0.72 | SIGMAR1 (0.30) | SIGMAR1OPRK1 | |
| SCHEMBL20970143 | 0.71 | LMNA (0.33) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969560-B2 | Process for the carbonylation of ethylenically unsaturated compounds, novel carbonylation ligands and catalyst systems incorporating such ligands | LUCITE INTERNATIONAL UK LIMITED (GB) | 2015-03-03 | — | — | US | disclosed |
| US-8816113-B2 | Process for the carbonylation of ethylenically unsaturated compounds, novel carbonylation ligands and catalyst systems incorporating such ligands | LUCITE INTERNATIONAL UK LIMITED (GB) | 2014-08-26 | — | — | US | disclosed |
| US-20120330016-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS, NOVEL CARBONYLATION LIGANDS AND CATALYST SYSTEMS INCORPORATING SUCH LIGANDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2012-12-27 | — | — | US | disclosed |
| US-20110137059-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS, NOVEL CARBONYLATION LIGANDS AND CATALYST SYSTEMS INCORPORATING SUCH LIGANDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330016-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS, NOVEL CARBONYLATION LIGANDS AND CATALYST SYSTEMS INCORPORATING SUCH LIGANDS | GRB2, CDK2, PDK1 | MEN1 1819/4885KMT2A 3411/4885NPSR1 3406/4885 |
| US-20110137059-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS, NOVEL CARBONYLATION LIGANDS AND CATALYST SYSTEMS INCORPORATING SUCH LIGANDS | CBR3, CBR1, XDH | MEN1 3503/4885KMT2A 3585/4885NPSR1 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.