Sugi Predict

Sugi Predict / Compounds / SCHEMBL125664

SCHEMBL125664

SCHEMBL125664

CC(O[C]=O)c1cc2c(cc1[N+](=O)[O-])OCO2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.54
▸ MEN1 O00255 4/20 0.54
▸ KMT2A Q03164 4/20 0.54
▸ L3MBTL1 Q9Y468 2/20 0.54
▸ POLB P06746 2/20 0.54
▸ MCL1 Q07820 1/20 0.54
▸ SRC P12931 1/20 0.52
▸ ALDH1A1 P00352 13/20 0.43
▸ LMNA P02545 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.42
▸ TXNRD1 Q16881 1/20 0.41
▸ TXNRD3 Q86VQ6 1/20 0.41
▸ TXNRD2 Q9NNW7 1/20 0.41
▸ KDM4E B2RXH2 7/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ CYP2D6 P10635 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17257753 1.00 MAPT (0.54) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL22927432 0.85 SRC (0.55) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL125665 0.81 SRC (0.51) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL880161 0.81 SRC (0.60) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL3326237 0.81 SRC (0.48) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL13347473 0.80 SRC (0.53) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL28607638 0.80 SRC (0.53) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL11986891 0.80 SRC (0.50) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL12050499 0.80 ALDH1A1 (0.60) MAPTMEN1KMT2AL3MBTL1POLB
SCHEMBL17257752 0.80 ALDH1A1 (0.34) MAPTMEN1KMT2AL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107002293-B Sequencing by synthesis using pulsed readout optics 艾比斯生物科学公司 2020-12-08 — — CN claimed
US-20200123605-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES, INC. 2020-04-23 — — US claimed
EP-3194643-B1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES INC (US) 2020-02-19 — — EP claimed
US-10550428-B2 Sequencing by synthesis using pulse read optics IBIS BIOSCIENCES, INC. (US) 2020-02-04 — — US claimed
US-20170247755-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES, INC. 2017-08-31 — — US claimed
EP-3194643-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS Ibis Biosciences, Inc. (US) 2017-07-26 — — EP claimed
WO-2016044391-A1 SEQUENCING BY SYNTHESIS USING PULSE READ OPTICS IBIS BIOSCIENCES, INC. (US) 2016-03-24 — — WO claimed
US-8975216-B2 Articles having localized molecules disposed thereon and methods of producing same PACIFIC BIOSCIENCES OF CALIFORNIA (US) 2015-03-10 — — US claimed
US-20090047712-A1 Chemically cleavable phosphoramidite linkers NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-02-19 — — US claimed
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 — — EP claimed
EP-1466663-A1 Quality control method for manufacturing nucleic acid arrays F. HOFFMANN-LA ROCHE AG (CH) 2004-10-13 — — EP claimed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 — — US claimed
US-20040191824-A1 Process for the synthesis of pyrazolopyrimidines EPOCH BIOSCIENCES, INC. 2004-09-30 — — US claimed
EP-1427743-A2 PROCESS FOR THE SYNTHESIS OF PYRAZOLOPYRIMIDINES Epoch Biosciences, Inc. (US) 2004-06-16 — — EP claimed
US-20030078413-A1 Process for the synthesis of pyrazolopyrimidines EPOCH BIOSCIENCES, INC. 2003-04-24 — — US claimed
WO-2003022859-A2 PROCESS FOR THE SYNTHESIS OF PYRAZOLOPYRIMIDINES EPOCH BIOSCIENCES, INC. (US) 2003-03-20 — — WO claimed
US-6489466-B2 PRODUCING IMMOBILIZED OLIGONUCLEOTIDES ON A SUBSTRATE BY COVALENTLY ATTACHING A FIRST NUCLEOTIDE OR OLIGONUCLEOTIDE VIA A C-5' OXYGEN OF THE NUCLEOTIDE TO THE SUBSTRATE; C-3'OXYGEN PROTECTED WITH PHOTO- OR CHEMICAL-LABILE GROUPS LINDEN TECHNOLOGIES, INC. 2002-12-03 — — US claimed
US-5744101-A Photolabile nucleoside protecting groups AFFYMAX TECHNOLOGIES N.V. (GB) 1998-04-28 — — US claimed
US-5412087-A Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces AFFYMAX TECHNOLOGIES N.V. (AN) 1995-05-02 — — US claimed
WO-1993022680-A1 SPATIALLY-ADDRESSABLE IMMOBILIZATION OF OLIGONUCLEOTIDES AND OTHER BIOLOGICAL POLYMERS ON SURFACES AFFYMAX TECHNOLOGIES N.V. (AN) 1993-11-11 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 MAPT 3220/4885MEN1 2823/4885KMT2A 2815/4885
US-20030078413-A1 Process for the synthesis of pyrazolopyrimidines DPYD, PNP, UMPS MAPT 3470/4885MEN1 3112/4885KMT2A 2128/4885
US-20090047712-A1 Chemically cleavable phosphoramidite linkers CPSF6, RNGTT, CPSF1 MAPT 3102/4885MEN1 1423/4885KMT2A 910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.