SCHEMBL125671

SCHEMBL125671

CC(=O)c1c(C)c2ccc(O)cc2oc1=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 7/20 0.71
ESR1 P03372 4/20 0.57
ESR2 Q92731 4/20 0.57
ERAP1 Q9NZ08 2/20 0.57
KDM4E B2RXH2 5/20 0.57
GLA P06280 5/20 0.57
GAA P10253 5/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 3/20 0.57
CASP1 P29466 3/20 0.57
CASP7 P55210 3/20 0.57
HSD17B10 Q99714 3/20 0.57
TSHR P16473 1/20 0.57
PDE2A O00408 1/20 0.54
NPSR1 Q6W5P4 2/20 0.53
NPC1 O15118 1/20 0.52
CCR4 P51679 1/20 0.52
CA12 O43570 1/20 0.51
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27872231 0.88 HSD17B3 (0.71) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL2226810 0.88 HSD17B3 (0.71) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL31281312 0.86 HSD17B3 (0.69) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL10849966 0.84 HSD17B3 (0.65) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL591899 0.83 HSD17B3 (1.00) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL31366988 0.83 HSD17B3 (1.00) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL7944663 0.83 SRC (0.53) HSD17B3KDM4EGLAGAAALDH1A1
SCHEMBL28096263 0.82 HSD17B3 (0.63) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL14916149 0.82 HSD17B3 (0.67) HSD17B3ESR1ESR2ERAP1KDM4E
SCHEMBL28446883 0.82 HSD17B3 (0.96) HSD17B3ESR1ESR2ERAP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3164196-B1 TOPICAL FORMULATIONS FOR UV PROTECTION TOPGENIX INC (US) 2021-08-18 EP claimed
EP-3164196-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TOPGENIX, INC. (US) 2017-05-10 EP claimed
US-20170119641-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TopGeniX, Inc. 2017-05-04 US claimed
WO-2015195546-A1 TOPICAL FORMULATIONS FOR UV PROTECTION TopGeniX, Inc. (US) 2015-12-23 WO claimed
EP-2916814-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN Colabs International Corporation (US) 2015-09-16 EP claimed
WO-2014074555-A1 COMPOSITION CONTAINING A CELLULOSE DERIVED CAPSULE WITH A SUNSCREEN CoLabs International Corporation (US) 2014-05-15 WO claimed
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen CoLabs International Corporation (US) 2014-05-08 US claimed
EP-2367852-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS Sederma (FR) 2011-09-28 EP claimed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US claimed
WO-2010067327-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS SEDERMA (FR) 2010-06-17 WO claimed
WO-2010044076-A2 COSMETIC AND TOPICAL USE OF XANTHOHUMOL INCLUDING BRIGHTENING SKIN COMPLEXION AND REDUCING CUTANEOUS REDNESS SEDERMA (FR) 2010-04-22 WO claimed
EP-1924254-A2 USE OF TELLURIUM COMPOUNDS FOR PROTECTION FROM ULTRA-VIOLET RADIATION Biomas Ltd. (IL) 2008-05-28 EP claimed
WO-2007032010-A2 USE OF TELLURIUM COMPOUNDS FOR PROTECTION FROM ULTRA-VIOLET RADIATION BIOMAS LTD. (IL) 2007-03-22 WO claimed
US-7186416-B2 Foamable pharmaceutical compositions and methods for treating a disorder STIEFEL LABORATORIES, INC. (US) 2007-03-06 US claimed
US-20060193789-A1 Surfacant, film forming agent, water, gas propellant; plant and animal extracts and oils; may include malathion FOAMIX LTD. (IL) 2006-08-31 US claimed
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2005-08-25 US claimed
US-11957769-B2 Polyhydroxy fullerene sunscreen active agents and compositions THE CLEVELAND CLINIC FOUNDATION (US) 2024-04-16 US disclosed
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents COLABS INT'L CORP. (US) 2024-03-28 US disclosed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP disclosed
US-4098881-A COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES THE PROCTER & GAMBLE COMPANY (US) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 HSD17B3 1022/4885ESR1 3636/4885ESR2 3066/4885
US-20140127275-A1 Composition Containing a Cellulose Derived Capsule With A Sunscreen MSH6, TYR, CUTA HSD17B3 1075/4885ESR1 4690/4885ESR2 4697/4885
US-20170119641-A1 TOPICAL FORMULATIONS FOR UV PROTECTION ERCC4, ERCC1, UNG HSD17B3 2782/4885ESR1 4465/4885ESR2 3139/4885
US-20050186158-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 HSD17B3 1022/4885ESR1 3636/4885ESR2 3066/4885
US-20240099948-A1 Compositions Comprising Silicon Dioxide-Based Particles Including One or More Agents MSN, LIPE, CUTA HSD17B3 3100/4885ESR1 4102/4885ESR2 4828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.