Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12588930 | 0.89 | KMT2A (0.34) | KMT2AKDM4EMAPTALDH1A1NPSR1 | |
| SCHEMBL12588934 | 0.88 | KDM4E (0.33) | KMT2AKDM4EATMMAPTALDH1A1 | |
| SCHEMBL11988006 | 0.82 | ALDH1A1 (0.35) | KMT2AKDM4EATMMAPTALDH1A1 | |
| SCHEMBL973485 | 0.81 | HNF4A (0.40) | KMT2AKDM4EATMMAPTALDH1A1 | |
| SCHEMBL29424688 | 0.81 | HNF4A (0.40) | KMT2AKDM4EATMMAPTALDH1A1 | |
| SCHEMBL12588944 | 0.78 | KDM4E (0.33) | KDM4EAHRABCG2NPC1RAB9A | |
| SCHEMBL14382011 | 0.74 | KDM4E (0.34) | KMT2AKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL2847420 | 0.71 | CYP1A2 (0.38) | KMT2AKDM4EATMALDH1A1POLB | |
| SCHEMBL14001440 | 0.71 | KMT2A (0.40) | KMT2AKDM4EATMMAPTALDH1A1 | |
| SCHEMBL12570267 | 0.71 | SMN1; SMN2 (0.43) | KDM4EMAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | FELIQS CORPORATION (JP) | 2019-06-27 | — | — | US | disclosed |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | SCIFLUOR LIFE SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-7964743-B2 | Catalyst for asymmetric synthesis, ligand for use therein, and process for producing optically active compound through asymmetric synthesis reaction using them | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-06-21 | — | — | US | disclosed |
| US-7964743-B2 | Catalyst for asymmetric synthesis, ligand for use therein, and process for producing optically active compound through asymmetric synthesis reaction using them | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20090156849-A1 | Catalyst for Asymmetric Synthesis, Ligand for Use Therein, and Process for Producing Optically Active Compound through Asymmetric Synthesis Reaction Using Them | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156849-A1 | Catalyst for Asymmetric Synthesis, Ligand for Use Therein, and Process for Producing Optically Active Compound through Asymmetric Synthesis Reaction Using Them | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1854802-A1 | CATALYST FOR ASYMMETRIC SYNTHESIS, LIGAND FOR USE THEREIN, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND THROUGH ASYMMETRIC SYNTHESIS REACTION USING THEM | Japan Science and Technology Agency (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194195-A1 | METHOD OF MAKING TETRAHYDRONAPHTHYRIDINYL NONANOIC ACID COMPOUNDS | NISCH, SLC10A1, AANAT | KMT2A 3422/4885KDM4E 4287/4885ATM 4755/4885 |
| US-20090156849-A1 | Catalyst for Asymmetric Synthesis, Ligand for Use Therein, and Process for Producing Optically Active Compound through Asymmetric Synthesis Reaction Using Them | ME1, ATIC, ADH1A | KMT2A 3016/4885KDM4E 3842/4885ATM 3596/4885 |
| US-10752625-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | KMT2A 3422/4885KDM4E 4287/4885ATM 4755/4885 |
| US-10253025-B2 | Method of making tetrahydronaphthyridinyl nonanoic acid compounds | NISCH, SLC10A1, AANAT | KMT2A 3422/4885KDM4E 4287/4885ATM 4755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.