Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 1/20 | 0.45 |
| ▸ | OGA | O60502 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164694 | 0.90 | CHRM2 (0.48) | OGAPNMTPTGS2NPC1RAB9A | |
| SCHEMBL12596097 | 0.87 | TRIM24 (0.51) | PNMTPTGS2NPC1RAB9APKM | |
| SCHEMBL18587031 | 0.83 | CA2 (0.59) | USP9XOGAPNMTPTGS2NPC1 | |
| SCHEMBL19692944 | 0.83 | USP9X (0.45) | USP9XOGAFFAR4NPC1RAB9A | |
| SCHEMBL14089191 | 0.81 | FFAR4 (0.57) | PTGS2FFAR4NPC1RAB9APKM | |
| SCHEMBL28856061 | 0.78 | HTR2C (0.51) | USP9XPTGS2PKMHTT | |
| SCHEMBL27898021 | 0.78 | PTGS2 (0.52) | PTGS2TRIM24BRD1BRPF1 | |
| SCHEMBL12157395 | 0.77 | PKM (0.61) | PTGS2FFAR4NPC1RAB9APKM | |
| SCHEMBL32670216 | 0.77 | PKM (0.61) | PTGS2FFAR4NPC1RAB9APKM | |
| SCHEMBL20336445 | 0.76 | ALDH1A1 (0.44) | USP9XFFAR4PKMCYP2C19CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493439-B1 | Proteasome inhibitors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2016-11-15 | — | — | US | disclosed |
| EP-2336107-A2 | Proton pump inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
| EP-1803709-A1 | PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2007-07-04 | — | — | EP | disclosed |