Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | BRD1 | O95696 | 1/20 | 0.51 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164691 | 0.90 | PKM (0.57) | KEAP1NFE2L2PKMPKLRMAPT | |
| SCHEMBL27898021 | 0.88 | PTGS2 (0.52) | TRIM24BRD1BRPF1KEAP1NFE2L2 | |
| SCHEMBL12595463 | 0.87 | USP9X (0.45) | TRIM24BRD1BRPF1PKMPTGS2 | |
| SCHEMBL91968 | 0.84 | TRIM24 (0.42) | TRIM24BRD1BRPF1KEAP1NFE2L2 | |
| SCHEMBL6674134 | 0.83 | CA2 (0.59) | TRIM24BRD1BRPF1KEAP1NFE2L2 | |
| SCHEMBL6307961 | 0.83 | KEAP1 (0.51) | TRIM24BRD1BRPF1KEAP1NFE2L2 | |
| SCHEMBL5747283 | 0.83 | PKM (0.49) | TRIM24BRD1BRPF1KEAP1NFE2L2 | |
| SCHEMBL3776295 | 0.83 | KEAP1 (0.54) | TRIM24BRD1BRPF1KEAP1NFE2L2 | |
| SCHEMBL14089191 | 0.81 | FFAR4 (0.57) | PKMPKLRPTGS2NPC1RAB9A | |
| SCHEMBL12157395 | 0.77 | PKM (0.61) | PKMPKLRPTGS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803709-B1 | PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2013-01-02 | — | — | EP | disclosed |
| EP-2336107-A2 | Proton pump inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2011-06-22 | — | — | EP | disclosed |