Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162983 | 0.84 | ADRB2 (0.39) | ADRB2MTNR1AMTNR1BNQO2HTR6 | |
| SCHEMBL18540667 | 0.82 | GPR84 (0.35) | ADRB2HTR6HTR2AHTR2CMEN1 | |
| SCHEMBL13592835 | 0.81 | HTR6 (0.53) | ADRB2HTR6HTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL3790913 | 0.80 | HTR6 (0.52) | ADRB2HTR6HTR2AHTR2CHTR1A | |
| SCHEMBL16286333 | 0.79 | HRH3 (0.45) | ADRB2HTR6HTR2AHTR2CHTR1A | |
| SCHEMBL1163641 | 0.76 | SLC6A4 (0.40) | ADRB2HTR6HTR2AHTR2CHTR1A | |
| SCHEMBL1163045 | 0.76 | ADRB2 (0.43) | ADRB2MTNR1AMTNR1BNQO2HTR2A | |
| SCHEMBL1163108 | 0.75 | ADRB2 (0.45) | ADRB2HTR2AMEN1KMT2A | |
| SCHEMBL1163095 | 0.74 | AKR1C3 (0.36) | MTNR1AMTNR1BNQO2MEN1KMT2A | |
| SCHEMBL12559305 | 0.74 | SMN1; SMN2 (0.52) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144090-A1 | COMPOUNDS AND METHODS OF USE THEREOF | AANAT, HNMT, INMT | ADRB2 613/4885MTNR1A 65/4885MTNR1B 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.