Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12607240 | 0.85 | L3MBTL1 (0.41) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12607247 | 0.83 | HDAC3 (0.40) | CYP1A2KMT2AALDH1A1CYP2C19 | |
| SCHEMBL12651031 | 0.83 | NPSR1 (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL9837170 | 0.83 | TRPA1 (0.47) | KMT2ACNR1HPGDSMN1; SMN2 | |
| SCHEMBL12607238 | 0.81 | MAPT (0.40) | KMT2AALDH1A1 | |
| SCHEMBL12607246 | 0.81 | ESR1 (0.42) | KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12651100 | 0.80 | PDE2A (0.43) | — | |
| SCHEMBL12607245 | 0.78 | TSHR (0.41) | CYP1A2KMT2APOLBALDH1A1HPGD | |
| SCHEMBL12607249 | 0.77 | CYP1A2 (0.41) | CYP1A2KMT2APOLBALDH1A1HPGD | |
| SCHEMBL12651028 | 0.77 | ALDH1A1 (0.46) | KMT2APOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642786-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-02-04 | — | — | US | disclosed |
| US-8642786-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20130204013-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| US-20130204013-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| US-8420849-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420849-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8399685-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399685-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20130060050-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20130060050-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20110124884-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20110124884-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060050-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | SULT1E1, CYP3A4, TKT | CYP1A2 92/4885KMT2A 2284/4885CNR1 2101/4885 |
| US-20130204013-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | TST, SULT1E1, GRHPR | CYP1A2 55/4885KMT2A 921/4885CNR1 2232/4885 |
| US-20110124884-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | TST, SULT1E1, GRHPR | CYP1A2 55/4885KMT2A 921/4885CNR1 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.