Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12607240 | 0.85 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL12607239 | 0.83 | CYP1A2 (0.47) | CNR1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL12651031 | 0.83 | NPSR1 (0.47) | HDAC4HDAC7HDAC5CNR2SMN1; SMN2 | |
| SCHEMBL12607247 | 0.83 | HDAC3 (0.40) | HDAC4HDAC7HDAC5GAAKMT2A | |
| SCHEMBL12607237 | 0.83 | SLC6A3 (0.51) | SLC6A4SLC6A3SLC6A2SMN1; SMN2 | |
| SCHEMBL12607241 | 0.81 | KMT2A (0.44) | SLC6A3HPGDSMN1; SMN2KMT2A | |
| SCHEMBL12607238 | 0.81 | MAPT (0.40) | SLC6A2KMT2A | |
| SCHEMBL12607246 | 0.81 | ESR1 (0.42) | L3MBTL1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL3518534 | 0.80 | CYP2C9 (0.51) | TRPA1L3MBTL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11849223 | 0.80 | PGR (0.44) | L3MBTL1SLC6A4SLC6A3GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246343-B1 | PROCESS FOR PRODUCTION OF THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-8642786-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-02-04 | — | — | US | disclosed |
| US-8642786-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20130204013-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| US-20130204013-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| US-8420849-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420849-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8399685-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-8399685-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20130060050-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20130060050-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20110124884-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20110124884-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-0256687-B1 | THIAZOLIDIN-4-ONE DERIVATIVES AND ACID ADDITION SALTS THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060050-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | SULT1E1, CYP3A4, TKT | TRPA1 1545/4885L3MBTL1 3016/4885BRD4 1421/4885 |
| US-20130204013-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | TST, SULT1E1, GRHPR | TRPA1 649/4885L3MBTL1 2553/4885BRD4 2139/4885 |
| US-20110124884-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | TST, SULT1E1, GRHPR | TRPA1 649/4885L3MBTL1 2553/4885BRD4 2139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.