Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20323484 | 0.81 | CA1 (0.52) | CA2CA1CA7CA14CA12 | |
| SCHEMBL15338342 | 0.81 | CA1 (0.44) | CA2CA1CA7CA14CA12 | |
| SCHEMBL709880 | 0.81 | PSIP1 (0.63) | CA2CA1CA7CA14CA12 | |
| SCHEMBL18264787 | 0.79 | ALDH1A1 (0.53) | CA2CA1CA7CA12CA6 | |
| SCHEMBL10266897 | 0.78 | PLCG1 (0.55) | CA2CA1CA14CA12CA9 | |
| SCHEMBL2446833 | 0.77 | PSIP1 (0.61) | PSIP1GAA | |
| SCHEMBL28906881 | 0.76 | CA2 (0.53) | CA2CA1CA7CA14CA12 | |
| SCHEMBL27306175 | 0.76 | ALDH1A1 (0.53) | CA2CA1CA7CA12CA6 | |
| SCHEMBL12610369 | 0.75 | CA1 (0.42) | CA2CA1GAAMMP13 | |
| SCHEMBL12610268 | 0.74 | CA1 (0.42) | CA2CA1CA7CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124603-A1 | Trioxane Dimer Sulfur Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124603-A1 | Trioxane Dimer Sulfur Compounds | HCCS, SQOR, SFXN1 | CA2 2086/4885CA1 3241/4885CA7 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.