Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264787 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAACYP2C19MEN1 | |
| SCHEMBL2444476 | 0.82 | PSIP1 (0.59) | PSIP1HSD11B1POLBALDH1A1TP53 | |
| SCHEMBL27933239 | 0.80 | PSIP1 (0.57) | PSIP1HSD11B1POLBALDH1A1TP53 | |
| SCHEMBL10266897 | 0.80 | PLCG1 (0.55) | PSIP1POLBTDP1CYP1A2GAA | |
| SCHEMBL29720307 | 0.79 | PSIP1 (0.55) | PSIP1HSD11B1POLBALDH1A1TP53 | |
| SCHEMBL778303 | 0.78 | PSIP1 (0.60) | PSIP1HSD11B1POLBALDH1A1TP53 | |
| SCHEMBL27306175 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAACYP2C19MEN1 | |
| SCHEMBL13513035 | 0.77 | PSIP1 (0.48) | PSIP1HSD11B1POLBALDH1A1TP53 | |
| SCHEMBL12610239 | 0.77 | CA2 (0.48) | PSIP1GAA | |
| SCHEMBL180713 | 0.77 | PSIP1 (1.00) | PSIP1HSD11B1POLBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575153-B2 | Pyridine-3-carboxyamide derivative | KOWA COMPANY, LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| EP-2380877-A1 | PYRIDINE-3-CARBOXYAMIDE DERIVATIVE | Kowa Company, Ltd. (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110237590-A1 | PYRIDINE-3-CARBOXYAMIDE DERIVATIVE | KOWA COMPANY, LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| US-20110124603-A1 | Trioxane Dimer Sulfur Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124603-A1 | Trioxane Dimer Sulfur Compounds | HCCS, SQOR, SFXN1 | PSIP1 928/4885HSD11B1 1765/4885POLB 1026/4885 |
| US-20110237590-A1 | PYRIDINE-3-CARBOXYAMIDE DERIVATIVE | JAK3, JAK1, UACA | PSIP1 1161/4885HSD11B1 4398/4885POLB 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.