Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820812 | 0.89 | MAPT (0.44) | MAPTKMT2AHCAR3SMN1; SMN2AKR1B10 | |
| SCHEMBL11142328 | 0.88 | HCAR3 (0.56) | MAPTKMT2AHCAR3SMN1; SMN2AKR1C3 | |
| SCHEMBL27864267 | 0.86 | SMN1; SMN2 (0.39) | MAPTKMT2AHCAR3SMN1; SMN2AKR1B10 | |
| SCHEMBL16868842 | 0.85 | DCTPP1 (0.49) | MAPTHCAR3SMN1; SMN2AKR1B10AKR1B1 | |
| SCHEMBL15064774 | 0.85 | SMN1; SMN2 (0.48) | MAPTKMT2AHCAR3SMN1; SMN2AKR1B10 | |
| SCHEMBL10907216 | 0.85 | SMN1; SMN2 (0.45) | MAPTKMT2AHCAR3SMN1; SMN2AKR1B10 | |
| SCHEMBL3988427 | 0.82 | SMN1; SMN2 (0.44) | MAPTKMT2AHCAR3SMN1; SMN2AKR1B10 | |
| SCHEMBL13211382 | 0.81 | MAPT (0.53) | MAPTKMT2AHCAR3SMN1; SMN2AKR1B10 | |
| SCHEMBL487216 | 0.80 | AKR1C3 (0.57) | MAPTKMT2ASMN1; SMN2AKR1B10AKR1B1 | |
| Iodide SCHEMBL9473610 | 0.79 | MAPT (0.42) | MAPTKMT2ASMN1; SMN2AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11737964-B2 | Hair color toning compositions, methods of use, and kits | L'OREAL (FR) | 2023-08-29 | — | — | US | claimed |
| US-20230099740-A1 | HAIR COLOR TONING COMPOSITIONS, METHODS OF USE, AND KITS | L'OREAL (FR) | 2023-03-30 | — | — | US | claimed |
| US-20210369582-A1 | METHODS AND COMPOSITIONS FOR REMOVING COLOR FROM COLOR-TREATED HAIR | L'OREAL (FR) | 2021-12-02 | — | — | US | claimed |
| US-11173102-B1 | Methods and compositions for removing color from color-treated hair | L'OREAL (FR) | 2021-11-16 | — | — | US | claimed |
| US-11154479-B1 | Methods of removing color from color-treated hair | L'OREAL (FR) | 2021-10-26 | — | — | US | claimed |
| CN-112955112-A | Two-component system for artificial hair coloring | 汉高股份有限及两合公司 | 2021-06-11 | — | — | CN | claimed |
| US-9993413-B2 | Keratin fibre dyeing composition | BEAUTY & BUSINESS S.P.A. (IT) | 2018-06-12 | — | — | US | claimed |
| EP-2658511-B1 | DYEING COMPOSITION FOR KERATIN FIBERS | KAO GERMANY GMBH (DE) | 2018-04-04 | — | — | EP | claimed |
| US-20170258695-A1 | KERATIN FIBRE DYEING COMPOSITION | BEAUTY & BUSINESS S.P.A. (IT) | 2017-09-14 | — | — | US | claimed |
| EP-2547315-B1 | COLOURING COMPOSITION FOR KERATIN FIBRES | KAO GERMANY GMBH (DE) | 2017-07-05 | — | — | EP | claimed |
| EP-1757326-A1 | Direct dying composition comprising insoluble oxygenated compounds and processes | L'Oréal (FR) | 2007-02-28 | — | — | EP | claimed |
| EP-1430876-A1 | Composition containing a direct dyestuff and a specific polymer for colouring of keratinic fibres, method for the preparation thereof and process of dyeing with such a composition | L'OREAL (FR) | 2004-06-23 | — | — | EP | claimed |
| EP-0646108-B1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1998-10-14 | — | — | EP | claimed |
| US-5792221-A | DYEING GRAY TO WHITE HAIR BLUE THROUGH PURPLISH-BLUE SHADES; WATER SOLUBILITY; WASH- AND COLORFASTNESS; WEATHERPROOFING; SWEAT RESISTANCE | L'OREAL (FR) | 1998-08-11 | — | — | US | claimed |
| EP-0646109-B1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-4555247-A | MIXTURE OF VIOLET AND YELLOW DYESTUFFS | L'OREAL (FR) | 1985-11-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737964-B2 | Hair color toning compositions, methods of use, and kits | CUTA, TAAR5, SHH | MAPT 3653/4885KMT2A 1404/4885HCAR3 992/4885 |
| US-11173102-B1 | Methods and compositions for removing color from color-treated hair | TYR, POLR1C, CYCS | MAPT 2581/4885KMT2A 1605/4885HCAR3 1577/4885 |
| US-20230099740-A1 | HAIR COLOR TONING COMPOSITIONS, METHODS OF USE, AND KITS | CUTA, TAAR5, SHH | MAPT 3653/4885KMT2A 1404/4885HCAR3 992/4885 |
| US-11154479-B1 | Methods of removing color from color-treated hair | TYR, IK, HLA-C | MAPT 2434/4885KMT2A 670/4885HCAR3 1513/4885 |
| US-20210369582-A1 | METHODS AND COMPOSITIONS FOR REMOVING COLOR FROM COLOR-TREATED HAIR | TYR, POLR1C, CYCS | MAPT 2581/4885KMT2A 1605/4885HCAR3 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.