Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | ACACA | Q13085 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646396 | 0.83 | PTPN1 (0.63) | PPARGPPARAMAPTALDH1A1NPC1 | |
| SCHEMBL422442 | 0.81 | ALOX15 (0.76) | ALOX15FFAR1PPARGPPARAPPARD | |
| SCHEMBL28715921 | 0.80 | ACACA (0.56) | ALOX15FFAR1PPARGPPARAPPARD | |
| SCHEMBL6808855 | 0.79 | ALOX15 (0.53) | ALOX15FFAR1PPARGPPARDACACA | |
| SCHEMBL23309077 | 0.79 | FFAR1 (0.72) | FFAR1FFAR4 | |
| SCHEMBL2780802 | 0.78 | ALOX15 (0.71) | ALOX15FFAR1PPARGPPARAPPARD | |
| SCHEMBL8682345 | 0.78 | PPARG (0.55) | FFAR1PPARGPPARAMAPTMEN1 | |
| SCHEMBL14539085 | 0.78 | NPC1 (0.61) | FFAR1PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL421532 | 0.78 | L3MBTL1 (0.59) | ALOX15FFAR1MAPTALDH1A1SMN1; SMN2 | |
| Alcohol SCHEMBL27641690 | 0.77 | ALOX15 (0.83) | ALOX15FFAR1MAPTPTPN7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152315-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | SYDDANSK UNIVERSITET | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152315-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | GPR119, INSR, GPR65 | ALOX15 763/4885FFAR1 6/4885PPARG 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.