Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.81 |
| ▸ | MMP9 | P14780 | 19/20 | 0.81 |
| ▸ | MMP14 | P50281 | 14/20 | 0.77 |
| ▸ | MMP1 | P03956 | 13/20 | 0.77 |
| ▸ | MMP3 | P08254 | 12/20 | 0.77 |
| ▸ | MMP13 | P45452 | 11/20 | 0.77 |
| ▸ | MMP8 | P22894 | 3/20 | 0.58 |
| ▸ | MMP16 | P51512 | 3/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18193394 | 0.88 | MMP2 (0.66) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1783672 | 0.87 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL18193637 | 0.85 | MMP2 (0.79) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1782200 | 0.82 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1785805 | 0.81 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL12605291 | 0.79 | MMP2 (0.51) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL12609294 | 0.78 | MMP2 (0.81) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL12609305 | 0.78 | MMP2 (0.81) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL3228660 | 0.77 | MMP2 (0.78) | MMP2MMP9MMP14MMP1MMP3 | |
| SCHEMBL1784100 | 0.76 | MMP2 (1.00) | MMP2MMP9MMP14MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117015-A1 | Diagnostic Agents Selective Against Metalloproteases | BRACCO IMAGING S.P.A. (IT) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117015-A1 | Diagnostic Agents Selective Against Metalloproteases | MMP3, MMP7, MMP9 | MMP2 9/4885MMP9 3/4885MMP14 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.