SCHEMBL1782200

SCHEMBL1782200

COc1ccc(-c2ccc(S(=O)(=O)N(OC(C)C)[C@H](CCN3C(=O)c4ccccc4C3=O)C(=O)NO)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 20/20 1.00
MMP9 P14780 20/20 1.00
MMP14 P50281 15/20 1.00
MMP1 P03956 14/20 1.00
MMP3 P08254 11/20 1.00
MMP13 P45452 9/20 1.00
ADAM17 P78536 2/20 0.55
ADAM10 O14672 1/20 0.55
MMP7 P09237 1/20 0.53
MMP8 P22894 2/20 0.51
NPC1 O15118 1/20 0.51
MMP12 P39900 1/20 0.51
MTOR P42345 1/20 0.51
RAB9A P51151 1/20 0.51
MMP16 P51512 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1783725 0.91 MMP2 (0.84) MMP2MMP9MMP14MMP1MMP3
SCHEMBL1782317 0.89 MMP2 (0.81) MMP2MMP9MMP14MMP1MMP3
SCHEMBL27812749 0.89 MMP2 (0.81) MMP2MMP9MMP14MMP1MMP3
SCHEMBL12650697 0.82 MMP2 (0.81) MMP2MMP9MMP14MMP1MMP3
SCHEMBL1783672 0.80 MMP2 (1.00) MMP2MMP9MMP14MMP1MMP3
SCHEMBL1785805 0.78 MMP2 (1.00) MMP2MMP9MMP14MMP1MMP3
SCHEMBL18193637 0.78 MMP2 (0.79) MMP2MMP9MMP14MMP1MMP3
SCHEMBL12609305 0.75 MMP2 (0.81) MMP2MMP9MMP14MMP1MMP3
SCHEMBL12609294 0.75 MMP2 (0.81) MMP2MMP9MMP14MMP1MMP3
SCHEMBL3228660 0.75 MMP2 (0.78) MMP2MMP9MMP14MMP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12582851-B2 Filter element for breathing apparatus, filter device, breathing apparatus, and use of filter element MANN+HUMMEL LIFE SCIENCES & ENVIRONMENT HOLDING SINGAPORE PTE. LTD. (SG) 2026-03-24 US disclosed
EP-4658395-A1 ARTICLES COMPRISING FILTER MEDIA WITH IRREGULAR STRUCTURE AND/OR REVERSIBLY STRETCHABLE LAYERS Hollingsworth & Vose Company (US) 2025-12-10 EP disclosed
US-12290706-B2 Respiratory protective device or face mask hygiene product, a method for the manufacture of reinforced textile part, nonwoven fabric part or their combination part, and a filter FORSSAN SUOJAINVALMISTUS OY (FI) 2025-05-06 US disclosed
WO-2024163873-A1 ARTICLES COMPRISING FILTER MEDIA WITH IRREGULAR STRUCTURE AND/OR REVERSIBLY STRETCHABLE LAYERS HOLLINGSWORTH & VOSE COMPANY (US) 2024-08-08 WO disclosed
US-20230415081-A1 ARTICLES COMPRISING FILTER MEDIA WITH IRREGULAR STRUCTURE AND/OR REVERSIBLY STRETCHABLE LAYERS HOLLINGSWORTH & VOSE COMPANY (US) 2023-12-28 US disclosed
US-20230390593-A1 A RESPIRATORY PROTECTIVE DEVICE OR FACE MASK HYGIENE PRODUCT, A METHOD FOR THE MANUFACTURE OF REINFORCED TEXTILE PART, NONWOVEN FABRIC PART OR THEIR COMBINATION PART, AND A FILTER FORSSAN SUOJAINVALMISTUS OY (FI) 2023-12-07 US disclosed
EP-4266935-A1 A RESPIRATORY PROTECTIVE DEVICE OR FACE MASK HYGIENE PRODUCT, A METHOD FOR THE MANUFACTURE OF REINFORCED TEXTILE PART, NONWOVEN FABRIC PART OR THEIR COMBINATION PART, AND A FILTER Forssan Suojainvalmistus Oy (FI) 2023-11-01 EP disclosed
CN-116549877-A Filter element for a breathing apparatus, filter device, breathing apparatus and use of a filter element 曼·胡默尔生命科学与环境德国有限责任公司 2023-08-08 CN disclosed
US-20230241426-A1 FILTER ELEMENT FOR BREATHING APPARATUS, FILTER DEVICE, BREATHING APPARATUS, AND USE OF FILTER ELEMENT MANN+HUMMEL LIFE SCIENCES & ENVIRONMENT HOLDING SINGAPORE PTE. LTD. (SG) 2023-08-03 US disclosed
EP-4218945-A1 FILTER ELEMENT FOR A BREATHING APPARATUS, FILTER DEVICE, BREATHING APPARATUS, AND USE OF A FILTER ELEMENT MANN+HUMMEL Vokes Air GmbH & Co. OHG (DE) 2023-08-02 EP disclosed
EP-4018862-A1 FILTER AND FACEBLANK FOR A RESPIRATORY PROTECTIVE DEVICE OR FACE MASK HYGIENE PRODUCT, RESPIRATORY PROTECTIVE DEVICE OR FACE MASK HYGIENE PRODUCT, AND METHOD FOR THE MANUFACTURE OF REINFORCED TEXTILE PART, NONWOVEN FABRIC PART OR THEIR COMBINATION PART Forssan Suojainvalmistus Oy (FI) 2022-06-29 EP disclosed
EP-2320954-B1 DIAGNOSTIC AGENTS SELECTIVE AGAINST METALLOPROTEASES BRACCO IMAGING SPA (IT) 2019-09-04 EP disclosed
US-9480758-B2 Diagnostic agents selective against metalloproteases BRACCO IMAGING S.P.A. (IT) 2016-11-01 US disclosed
US-8329751-B2 Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors BRACCO IMAGING S.P.A. (IT) 2012-12-11 US disclosed
US-20110124653-A1 ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS BRACCO IMAGING S.P.A. (IT) 2011-05-26 US disclosed
US-20110117015-A1 Diagnostic Agents Selective Against Metalloproteases BRACCO IMAGING S.P.A. (IT) 2011-05-19 US disclosed
US-20100087505-A1 Compounds Having Aryl-Sulphonamidic Structure Useful As Metalloproteases Inhibitors BRACCO IMAGING S.P.A. (IT) 2010-04-08 US disclosed
EP-2149568-A1 ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS Bracco Imaging S.p.A (IT) 2010-02-03 EP disclosed
EP-2147684-A1 Diagnostic Agents Selective Against Metalloproteases Bracco Imaging S.p.A (IT) 2010-01-27 EP disclosed
EP-1972617-A1 Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors Bracco Imaging, S.P.A. (IT) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124653-A1 ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS MMP9, MMP1, MMP2 MMP2 3/4885MMP9 1/4885MMP14 33/4885
US-20110117015-A1 Diagnostic Agents Selective Against Metalloproteases MMP3, MMP7, MMP9 MMP2 9/4885MMP9 3/4885MMP14 20/4885
US-12582851-B2 Filter element for breathing apparatus, filter device, breathing apparatus, and use of filter element EXOSC9, PSMD9, EIF4E MMP2 1904/4885MMP9 1323/4885MMP14 2049/4885
US-20100087505-A1 Compounds Having Aryl-Sulphonamidic Structure Useful As Metalloproteases Inhibitors MMP9, MMP1, ARSA MMP2 9/4885MMP9 1/4885MMP14 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.