Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12656308 | 0.83 | NEK2 (0.66) | NEK2TSHROPRM1OPRD1OPRK1 | |
| SCHEMBL15694871 | 0.81 | NEK2 (0.34) | NEK2TSHR | |
| SCHEMBL15478459 | 0.81 | NEK2 (0.68) | NEK2OPRM1KDM4E | |
| SCHEMBL12624271 | 0.77 | NEK2 (0.45) | NEK2OPRM1 | |
| SCHEMBL12673040 | 0.76 | TSHR (0.41) | TSHROPRM1OPRD1OPRK1KDM4E | |
| SCHEMBL12627243 | 0.74 | GAA (0.54) | TSHRKDM4EGAAALDH1A1 | |
| SCHEMBL21739459 | 0.74 | CYP11B1 (0.47) | OPRM1OPRD1OPRK1KDM4EGAA | |
| SCHEMBL12656159 | 0.72 | TSHR (0.39) | TSHRKDM4EGAA | |
| SCHEMBL22256990 | 0.71 | PDCD1LG2 (0.42) | OPRM1OPRD1OPRK1CRBNKDM4E | |
| SCHEMBL21673277 | 0.69 | PDCD1LG2 (0.38) | NEK2TSHROPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105487-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | PAIN THERAPEUTICS | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105487-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | FLNA, FLNB, FPR1 | NEK2 837/4885TSHR 4404/4885OPRM1 27/4885 |
| US-20110105481-A1 | FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC | FLNA, FLNB, OPRK1 | NEK2 883/4885TSHR 4455/4885OPRM1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.