Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 1/20 | 0.42 |
| ▸ | TAF1 | P21675 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1266199 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MCL1CES2BCHECES1 | |
| SCHEMBL10702898 | 0.79 | NPSR1 (0.60) | BRD1TAF1BRPF1ALDH1A1MCL1 | |
| SCHEMBL29434909 | 0.76 | TYMS (0.64) | BRD1TAF1BRPF1TYMS | |
| SCHEMBL600271 | 0.76 | TYMS (0.64) | BRD1TAF1BRPF1TYMS | |
| SCHEMBL5750580 | 0.75 | PARP1 (0.66) | BRD1TAF1BRPF1ALDH1A1MCL1 | |
| SCHEMBL5683684 | 0.75 | PABPC1 (0.63) | BRD1TAF1BRPF1ALDH1A1MCL1 | |
| SCHEMBL7706718 | 0.74 | ERCC1 (0.70) | BRD1TAF1BRPF1ALDH1A1MEN1 | |
| SCHEMBL8927321 | 0.72 | BRD1 (0.59) | BRD1TAF1BRPF1ALDH1A1MEN1 | |
| SCHEMBL10703784 | 0.72 | BRD1 (0.52) | BRD1TAF1BRPF1ALDH1A1MEN1 | |
| SCHEMBL14159192 | 0.69 | POLB (0.60) | BRD1TAF1BRPF1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027179-A2 | ANTIRETROVIRAL BASES | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | disclosed |