Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | EIF4E | P06730 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TOP1 | P11387 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385747 | 1.00 | LMNA (0.57) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL2481555 | 1.00 | LMNA (0.57) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL7213155 | 1.00 | LMNA (0.57) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL12669988 | 1.00 | LMNA (0.57) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL8722885 | 1.00 | LMNA (0.57) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL15916868 | 0.87 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL28863454 | 0.84 | TP53 (0.48) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL17993314 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1TSHRTHPO | |
| SCHEMBL24024486 | 0.82 | ATIC (0.62) | SMN1; SMN2ADORA1 | |
| SCHEMBL29687021 | 0.82 | ATIC (0.62) | SMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117054-A1 | USE OF RIBAVIRIN IN BLOOD COAGULATION DISORDER | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110045535-A1 | Activator for Blood Coagulation Factor VII Promoter and Utilization of the Same | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2201953-A1 | USE OF RIBAVIRIN IN BLOOD COAGULATION DISORDER | National University Corporation Nagoya University (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-2198870-A1 | ACTIVATOR FOR BLOOD COAGULATION FACTOR VII PROMOTER AND UTILIZATION OF THE SAME | National University Corporation Nagoya University (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20100129317-A1 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VIRAL POLYMERASES | SOUTHERN RESEARCH INSTITUTE (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2008067002-A2 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VARIAL POLYMERASES | SOUTHERN RESEARCH INSTITUTE (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129317-A1 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VIRAL POLYMERASES | RNASEH1, RNASEL, POLR2E | LMNA 739/4885SMN1; SMN2 3616/4885ALDH1A1 2684/4885 |
| US-20110045535-A1 | Activator for Blood Coagulation Factor VII Promoter and Utilization of the Same | F7, F8, HABP2 | LMNA 2396/4885SMN1; SMN2 3898/4885ALDH1A1 2278/4885 |
| US-20110117054-A1 | USE OF RIBAVIRIN IN BLOOD COAGULATION DISORDER | F2, SERPINC1, F8 | LMNA 1195/4885SMN1; SMN2 864/4885ALDH1A1 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.