Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.55 |
| ▸ | DHFR | P00374 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21734369 | 0.93 | HSPA5 (0.62) | HSPA5DHFRGABRA1GABRB2PTPN1 | |
| SCHEMBL2387607 | 0.93 | DHFR (0.54) | HSPA5DHFRGABRA1GABRB2PTPN1 | |
| SCHEMBL30003843 | 0.93 | DHFR (0.54) | HSPA5DHFRGABRA1GABRB2PTPN1 | |
| SCHEMBL581480 | 0.91 | GABRA1 (0.52) | HSPA5DHFRGABRA1GABRB2SHBG | |
| Dimethylamine SCHEMBL10751129 | 0.88 | HSPA5 (0.52) | HSPA5DHFRGABRA1GABRB2SHBG | |
| SCHEMBL4364941 | 0.88 | DHFR (0.53) | HSPA5DHFRGABRA1GABRB2PTPN1 | |
| SCHEMBL22408778 | 0.87 | DHFR (0.50) | HSPA5DHFRGABRA1GABRB2PTPN1 | |
| SCHEMBL30320252 | 0.86 | ESR1 (0.52) | HSPA5DHFRGABRA1GABRB2PTPN1 | |
| SCHEMBL4053628 | 0.86 | ESR1 (0.52) | HSPA5DHFRGABRA1GABRB2PTPN1 | |
| SCHEMBL3194655 | 0.85 | SHBG (0.55) | HSPA5DHFRGABRA1GABRB2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273426-B1 | Encapsulated compositions | FRITZ INDUSTRIES, INC (US) | 2012-09-25 | — | — | US | disclosed |