SCHEMBL4053628

SCHEMBL4053628

CCc1cc(Cc2ccc(O)cc2)cc(Cc2ccc(O)cc2)c1O

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
PTPN1 P18031 2/20 0.47
PTPN2 P17706 1/20 0.47
PTPN6 P29350 1/20 0.47
DHFR P00374 2/20 0.46
KEAP1 Q14145 1/20 0.44
HSPA5 P11021 1/20 0.43
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
KMT2A Q03164 2/20 0.40
BACE1 P56817 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
SHBG P04278 1/20 0.39
IDH1 O75874 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30320252 1.00 ESR1 (0.52) ESR1ESR2PTPN1PTPN2PTPN6
SCHEMBL22500515 0.90 ESR1 (0.52) ESR1ESR2PTPN1PTPN2PTPN6
SCHEMBL6847088 0.90 ESR1 (0.64) ESR1ESR2PTPN1PTPN2PTPN6
SCHEMBL4056329 0.90 ESR1 (0.64) ESR1ESR2PTPN1PTPN2PTPN6
SCHEMBL30003843 0.88 DHFR (0.54) PTPN1PTPN2PTPN6DHFRHSPA5
SCHEMBL2387607 0.88 DHFR (0.54) PTPN1PTPN2PTPN6DHFRHSPA5
SCHEMBL28929859 0.87 AMY1A (0.49) ESR1ESR2DHFRKEAP1HSPA5
SCHEMBL12680554 0.86 HSPA5 (0.55) PTPN1PTPN2PTPN6DHFRHSPA5
SCHEMBL10024009 0.86 SHBG (0.58) ESR1ESR2PTPN1PTPN2PTPN6
SCHEMBL19621088 0.84 ESR1 (0.42) ESR1ESR2DHFRKEAP1HSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ESR1 392/4885ESR2 895/4885PTPN1 2608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.