SCHEMBL1270034

SCHEMBL1270034

Cc1cc(-c2cc(C)c(N)c(C)c2)ccc1N

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 10/20 0.81
TDP1 Q9NUW8 9/20 0.81
ALDH1A1 P00352 9/20 0.81
TSHR P16473 5/20 0.81
TP53 P04637 3/20 0.67
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.42
ALOX15 P16050 3/20 0.42
THRB P10828 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
PKM P14618 1/20 0.42
HSD17B10 Q99714 4/20 0.41
S100B P04271 1/20 0.41
MAPK1 P28482 3/20 0.40
APP P05067 1/20 0.40
SKP2 Q13309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL310203 0.90 CYP3A4 (0.90) CYP3A4TDP1ALDH1A1TSHRTP53
SCHEMBL29764072 0.90 CYP3A4 (0.90) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL49414 0.90 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL29386552 0.90 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL29365329 0.90 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL11189493 0.87 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL20547383 0.87 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL22129692 0.87 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL6009632 0.87 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53
Orthotolidine SCHEMBL867121 0.87 CYP3A4 (0.94) CYP3A4TDP1ALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119258129-A Extract for treating psoriasis and preparation method and application thereof 中国中医科学院广安门医院 2025-01-07 CN disclosed
CN-117929728-A Immunomagnetic bead detection kit for pig transmissible gastroenteritis virus IgG antibody and application thereof 河南农业大学 2024-04-26 CN disclosed
US-20240016921-A1 ANTIGEN SPECIFIC IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE VAKSTON, INC. 2024-01-18 US disclosed
EP-4248983-A2 ANTIGEN SPECIFIC IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE Akston Biosciences Corporation (US) 2023-09-27 EP disclosed
US-11707517-B2 Antigen specific immunotherapy for COVID-19 fusion proteins and methods of use AKSTON BIOSCIENCES CORPORATION (US) 2023-07-25 US disclosed
EP-3972987-B1 ANTIGEN SPECIFIC IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE AKSTON BIOSCIENCES CORP (US) 2023-06-07 EP disclosed
EP-3972987-A1 ANTIGEN SPECIFIC IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE Akston Biosciences Corporation (US) 2022-03-30 EP disclosed
US-20220088182-A1 ANTIGEN SPECIFIC IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE VAKSTON, INC. 2022-03-24 US disclosed
WO-2021207599-A9 ANTIGEN SPECIFIC IMMUNOTHERAPY FOR COVID-19 FUSION PROTEINS AND METHODS OF USE AKSTON BIOSCIENCES CORPORATION (US) 2022-01-06 WO disclosed
US-11213581-B2 Antigen specific immunotherapy for COVID-19 fusion proteins and methods of use AKSTON BIOSCIENCES CORPORATION (US) 2022-01-04 US disclosed
US-20170071200-A1 SELF INDICATING ANTIMICROBIAL CHEMISTRY ECOLAB USA INC. 2017-03-16 US disclosed
EP-2623987-B1 Solid phase multi-analyte assay PSYCHEMEDICS CORP (US) 2015-12-30 EP disclosed
EP-2623987-A1 Solid phase multi-analyte assay Psychemedics Corporation (US) 2013-08-07 EP disclosed
EP-2281204-A1 SOLID PHASE MULTI-ANALYTE ASSAY Psychemedics Corporation (US) 2011-02-09 EP disclosed
US-20100279941-A1 CD36 MODULATION AND USES THEREOF VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) 2010-11-04 US disclosed
WO-2009134855-A1 SOLID PHASE MULTI-ANALYTE ASSAY PSYCHEMEDICS CORPORATION (US) 2009-11-05 WO disclosed
US-20050026826-A1 Feline proinsulin, insulin and constituent peptides UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC., THE 2005-02-03 US disclosed
EP-0407172-B1 Aromatic polyimide separation membrane MITSUBISHI CHEM IND (JP) 1994-02-23 EP disclosed
US-5112941-A A fluorinated membranes with high selectivity MITSUBISHI KASEI CORPORATION (JP) 1992-05-12 US disclosed
EP-0407172-A1 Aromatic polyimide separation membrane MITSUBISHI KASEI CORPORATION (JP) 1991-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279941-A1 CD36 MODULATION AND USES THEREOF FABP3, TNNI3, SCARB1 CYP3A4 4500/4885TDP1 4093/4885ALDH1A1 1464/4885
US-20170071200-A1 SELF INDICATING ANTIMICROBIAL CHEMISTRY HPD, HAO2, OAT CYP3A4 427/4885TDP1 1985/4885ALDH1A1 546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.