SCHEMBL12716

SCHEMBL12716

CC(C)CCN1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.48
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT8 Q9NR22 1/20 0.42
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
PSMB1 P20618 1/20 0.39
PSMB5 P28074 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074673 1.00 HRH3 (0.48) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL24724037 1.00 HRH3 (0.48) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL172560 0.97 CARM1 (0.44) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL441047 0.92
SCHEMBL20438382 0.86 ALOX15 (0.38)
SCHEMBL12000726 0.86
SCHEMBL6057217 0.86 ALOX15 (0.38)
SCHEMBL439729 0.85 HRH3 (0.56) HRH3MAPTCYP1A2
SCHEMBL172955 0.85 HRH3 (0.56) HRH3MAPTCYP1A2
Acetic Acid SCHEMBL31035858 0.84 ALDH1A1 (0.44) ALDH1A1POLBMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 606 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787785-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2023-10-17 US claimed
US-20230108325-A1 Pyrazolopyridine Derivatives and Uses thereof NOVARTIS AG (CH) 2023-04-06 US claimed
EP-3676221-A1 METHOD FOR MANUFACTURING VERTICALLY ALIGNED CARBON NANOTUBES, AND ELECTROCHEMICAL CAPACITORS USING THESE NANOTUBES AS ELECTRODES Nawatechnologies (FR) 2020-07-08 EP claimed
EP-3607571-A1 PROCESS FOR MANUFACTURING ELECTROCHEMICAL CAPACITORS Nawatechnologies (FR) 2020-02-12 EP claimed
WO-2019043320-A1 METHOD FOR MANUFACTURING VERTICALLY ALIGNED CARBON NANOTUBES, AND ELECTROCHEMICAL CAPACITORS USING THESE NANOTUBES AS ELECTRODES NAWATECHNOLOGIES (FR) 2019-03-07 WO claimed
US-20250282762-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2025-09-11 US disclosed
US-12252482-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2025-03-18 US disclosed
CN-119371422-A Methods for preparing Toll-like receptor modulator compounds 吉利德科学公司 2025-01-28 CN disclosed
US-12202848-B2 Phosphoramidite activator FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2025-01-21 US disclosed
US-20250002479-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2025-01-02 US disclosed
US-12172984-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2024-12-24 US disclosed
CN-114269744-B Methods for preparing Toll-like receptor modulator compounds 吉利德科学公司 2024-10-18 CN disclosed
WO-2001051527-A1 PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051526-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075202-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
CN-1061963-A Be used as the croak pyridine class of the 4-replacement of medicine SMITH KLINE FRENCH LAB (GB) 1992-06-17 CN disclosed
US-4041052-A DYES POLYESTER FIBERS ORANGE OR RED-VIOLET CIBA-GEIGY CORPORATION (US) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787785-B2 Pyrazolopyridine derivatives and uses thereof HBZ, ZFX, WIZ HRH3 4374/4885CARM1 1093/4885PRMT6 1775/4885
US-12172984-B2 Pyrazolopyridine derivatives and uses thereof HBZ, ZFX, WIZ HRH3 4374/4885CARM1 1093/4885PRMT6 1775/4885
US-12252482-B2 Pyrazolopyridine derivatives and uses thereof HBZ, ZFX, WIZ HRH3 4374/4885CARM1 1093/4885PRMT6 1775/4885
US-20250282762-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF HBZ, ZFX, WIZ HRH3 4374/4885CARM1 1093/4885PRMT6 1775/4885
US-12202848-B2 Phosphoramidite activator ITPA, INPP5D, INPP5B HRH3 2265/4885CARM1 2442/4885PRMT6 2943/4885
US-20230108325-A1 Pyrazolopyridine Derivatives and Uses thereof HBZ, ZFX, WIZ HRH3 4374/4885CARM1 1093/4885PRMT6 1775/4885
US-20250002479-A1 PYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF HBZ, ZFX, WIZ HRH3 4374/4885CARM1 1093/4885PRMT6 1775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.