SCHEMBL172560

SCHEMBL172560

CC(C)CCN1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
PRMT8 Q9NR22 1/20 0.44
HRH3 Q9Y5N1 1/20 0.43
MAPT P10636 1/20 0.39
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MCL1 Q07820 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12716 0.97 HRH3 (0.48) CARM1PRMT6PRMT8HRH3MAPT
SCHEMBL8074673 0.97 HRH3 (0.48) CARM1PRMT6PRMT8HRH3MAPT
SCHEMBL24724037 0.97 HRH3 (0.48) CARM1PRMT6PRMT8HRH3MAPT
SCHEMBL441047 0.94
SCHEMBL12000726 0.88
SCHEMBL6057217 0.88 ALOX15 (0.38)
SCHEMBL20438382 0.88 ALOX15 (0.38)
Acetic Acid SCHEMBL31035858 0.87 ALDH1A1 (0.44) MAPTKDM4EALDH1A1MCL1L3MBTL1
SCHEMBL439509 0.84 HRH3 (0.52) CARM1PRMT6PRMT8HRH3MAPT
SCHEMBL17806050 0.84 CHKA (0.43) PRMT6KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12202848-B2 Phosphoramidite activator FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2025-01-21 US disclosed
US-20240229026-A1 CHIRAL CONTROL WAVE LIFE SCIENCES LTD. (SG) 2024-07-11 US disclosed
US-12029739-B2 SHP2 inhibitor and use thereof KANAPH THERAPEUTICS INC. (KR) 2024-07-09 US disclosed
US-12024484-B2 Lipid formulations for gene editing VERVE THERAPEUTICS, INC. (US) 2024-07-02 US disclosed
US-20240208967-A1 Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof INVENTISBIO CO LTD (CN) 2024-06-27 US disclosed
US-20240166674-A1 PHOSPHORAMIDITE ACTIVATOR FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2024-05-23 US disclosed
EP-4140991-B1 INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES PROMEGA CORP (US) 2024-05-15 EP disclosed
CN-114555617-B Phosphoramidite activators 富士胶片和光纯药株式会社 2024-03-08 CN disclosed
EP-4047004-B1 PHOSPHORAMIDITE ACTIVATOR FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2024-03-06 EP disclosed
US-20240066029-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS ARRAY BIOPHARMA INC. 2024-02-29 US disclosed
WO-2001051527-A1 PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2001051526-A1 PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION EASTMAN CHEMICAL COMPANY (US) 2001-07-19 WO disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075202-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
EP-0264499-B1 SULFONATED POLY(ARYL ETHER) RESINS AND INTERMEDIATE SILYL SULFONATE DERIVATIVES; METHODS OF MAKING THEM, AND MEMBRANES FORMED FROM THE RESINS AMOCO CORPORATION (an Indiana corp.) (US) 1990-08-01 EP disclosed
EP-0264499-A1 Sulfonated poly(aryl ether) resins and intermediate silyl sulfonate derivatives; methods of making them, and membranes formed from the resins AMOCO CORPORATION (an Indiana corp.) (US) 1988-04-27 EP disclosed
US-4625000-A SULFONATED WITH SILYL HALOSULFONATE THEN CLEAVAGE OF SILYL GROUP UNION CARBIDE CORPORATION (US) 1986-11-25 US disclosed
US-4450246-A TERTIARY AMINE SALT W. R. GRACE & CO. (US) 1984-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024484-B2 Lipid formulations for gene editing LIPA, LIPC, ABHD16A CARM1 2953/4885PRMT6 2886/4885PRMT8 3444/4885
US-20240166674-A1 PHOSPHORAMIDITE ACTIVATOR ITPA, INPP5D, INPP5B CARM1 2442/4885PRMT6 2943/4885PRMT8 1804/4885
US-20240208967-A1 Pyrimidine or Pyridine Compounds, Preparation Method Therefor and Pharmaceutical Uses Thereof EGFR, WEE1, DPYD CARM1 4365/4885PRMT6 3088/4885PRMT8 1608/4885
US-20240229026-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 CARM1 2649/4885PRMT6 1784/4885PRMT8 2659/4885
US-12202848-B2 Phosphoramidite activator ITPA, INPP5D, INPP5B CARM1 2442/4885PRMT6 2943/4885PRMT8 1804/4885
US-12029739-B2 SHP2 inhibitor and use thereof PTPN1, PTPN5, PTPN2 CARM1 2000/4885PRMT6 1285/4885PRMT8 1774/4885
US-20240066029-A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS RET, ROR1, BRAF CARM1 216/4885PRMT6 185/4885PRMT8 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.