Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 4/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30818068 | 0.89 | IDH1 (0.46) | PGK1PGK2IDH1IDH2P2RX7 | |
| SCHEMBL1111072 | 0.89 | IDH1 (0.46) | PGK1PGK2IDH1IDH2P2RX7 | |
| Hydrochloric Acid SCHEMBL1192288 | 0.87 | IDH1 (0.45) | PGK1PGK2IDH1IDH2P2RX7 | |
| Hydrochloric Acid SCHEMBL30818101 | 0.87 | IDH1 (0.45) | PGK1PGK2IDH1IDH2P2RX7 | |
| SCHEMBL12873766 | 0.85 | NOS3 (0.48) | IRAK4CYP3A4TSHRNOS3NOS2 | |
| SCHEMBL29168104 | 0.84 | IRAK4 (0.33) | IRAK4PGK1PGK2CYP3A4TSHR | |
| SCHEMBL1111062 | 0.84 | IRAK4 (0.33) | IRAK4CYP3A4TSHRAKT1AKT2 | |
| SCHEMBL28413544 | 0.80 | TAAR1 (0.37) | CYP3A4TAAR1ALDH1A1 | |
| SCHEMBL24915287 | 0.79 | CCR1 (0.38) | IRAK4PGK1PGK2PARP1CCR1 | |
| SCHEMBL1111352 | 0.79 | CTSK (0.39) | IRAK4IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359680-B2 | Ruthenium or osmium complexes and their uses as catalysts for water oxidation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2016-06-07 | — | — | US | disclosed |
| US-20150073143-A1 | Ruthenium or Osmium Complexes and Their Uses as Catalysts for Water Oxidation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-03-12 | — | — | US | disclosed |
| US-8871078-B2 | Ruthenium or osmium complexes and their uses as catalysts for water oxidation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140034505-A1 | Ruthenium or Osmium Complexes and Their Uses as Catalysts for Water Oxidation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-02-06 | — | — | US | disclosed |
| US-8524903-B2 | Ruthenium or osmium complexes and their uses as catalysts for water oxidation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-09-03 | — | — | US | disclosed |
| US-20110042227-A1 | Ruthenium or Osmium Complexes and Their Uses as Catalysts for Water Oxidation | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073143-A1 | Ruthenium or Osmium Complexes and Their Uses as Catalysts for Water Oxidation | PPOX, AQP1, AQP3 | IRAK4 4262/4885PGK1 2398/4885PGK2 1792/4885 |
| US-20110042227-A1 | Ruthenium or Osmium Complexes and Their Uses as Catalysts for Water Oxidation | PPOX, AQP1, AQP3 | IRAK4 4262/4885PGK1 2398/4885PGK2 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.