Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HPD | P32754 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746139 | 0.80 | VEGFA (0.47) | HDAC4MAOBMAOAATM | |
| SCHEMBL12745892 | 0.79 | GSTP1 (0.49) | GSTP1MRGPRX4BRD4GRM5NR4A2 | |
| SCHEMBL379281 | 0.76 | MAOB (0.67) | GSTP1MRGPRX4NR4A2MAOBMAOA | |
| SCHEMBL2137838 | 0.74 | MRGPRX4 (0.69) | GSTP1MRGPRX4NR4A2HDAC4NAAA | |
| SCHEMBL16346074 | 0.73 | GSTP1 (0.66) | GSTP1MRGPRX4NR4A2HDAC4NAAA | |
| SCHEMBL4095412 | 0.72 | MAOA (0.77) | GSTP1BRD4HPDMAOBMAOA | |
| SCHEMBL3786472 | 0.72 | MAOB (0.68) | GSTP1MRGPRX4NR4A2HDAC4NAAA | |
| SCHEMBL30426715 | 0.72 | MAOB (0.68) | GSTP1MRGPRX4NR4A2HDAC4NAAA | |
| SCHEMBL7346174 | 0.70 | MRGPRX4 (0.64) | GSTP1MRGPRX4NR4A2HDAC4NAAA | |
| SCHEMBL12746147 | 0.69 | PGR (0.49) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071178-A1 | Methods and Compounds for Modulating Cannabinoid Activity | NORTHEASTERN UNIVERSITY (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071178-A1 | Methods and Compounds for Modulating Cannabinoid Activity | FAAH, FAAH2, CNR2 | GSTP1 2199/4885MRGPRX4 177/4885BRD4 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.