Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | PRF1 | P14222 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746139 | 0.81 | VEGFA (0.47) | VEGFACLK4MAOB | |
| SCHEMBL12745919 | 0.75 | CHEK1 (0.50) | PGRCHEK1XDHSLC22A12AR | |
| SCHEMBL12746153 | 0.74 | TDP2 (0.47) | PGRCHEK1VEGFAHRH3CLK4 | |
| SCHEMBL12746145 | 0.74 | GSTP1 (0.47) | VEGFAMAOB | |
| SCHEMBL2154026 | 0.71 | CLK4 (0.65) | PGRXDHSLC22A12PTPN5ADRA2C | |
| SCHEMBL4423216 | 0.70 | PGR (0.56) | PGRCHEK1XDHSLC22A12PRF1 | |
| SCHEMBL12746146 | 0.70 | VEGFA (0.43) | CHEK1PRF1VEGFAPDK2 | |
| SCHEMBL12746160 | 0.69 | VEGFA (0.43) | VEGFAAR | |
| SCHEMBL12746142 | 0.69 | GSTP1 (0.49) | MAOB | |
| SCHEMBL27787243 | 0.69 | CLK4 (0.63) | PGRXDHSLC22A12PTPN5ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071178-A1 | Methods and Compounds for Modulating Cannabinoid Activity | NORTHEASTERN UNIVERSITY (US) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071178-A1 | Methods and Compounds for Modulating Cannabinoid Activity | FAAH, FAAH2, CNR2 | PGR 2116/4885CHEK1 3378/4885XDH 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.