Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.48 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LPO | P22079 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14412223 | 0.92 | NMT1 (0.52) | TGFBR1TGFBR2NMT1RIPK2BRD4 | |
| SCHEMBL17264894 | 0.87 | NMT1 (0.52) | TGFBR1TGFBR2NMT1RIPK2BRD4 | |
| SCHEMBL3970148 | 0.84 | MAP4K4 (0.46) | NMT1RIPK2POLBMAPTBRD4 | |
| SCHEMBL29711750 | 0.84 | HSD17B2 (0.48) | NMT1RIPK2NTRK1 | |
| SCHEMBL2616608 | 0.84 | HSD17B2 (0.48) | NMT1RIPK2NTRK1 | |
| SCHEMBL12320076 | 0.84 | KDR (0.47) | TGFBR1NMT1RIPK2POLBBRD4 | |
| SCHEMBL3489826 | 0.84 | NMT1 (0.47) | TGFBR1NMT1RIPK2MAPTBRD4 | |
| SCHEMBL28469346 | 0.84 | NMT1 (0.44) | TGFBR1TGFBR2NMT1RIPK2BRD4 | |
| SCHEMBL3488664 | 0.84 | IDO1 (0.49) | NMT1RIPK2POLBMAPTBRD4 | |
| SCHEMBL23571873 | 0.82 | F2 (0.49) | NMT1RIPK2POLBBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110964062-A | Iridium complex and organic electroluminescent device using the same | 机光科技股份有限公司 | 2020-04-07 | — | — | CN | disclosed |
| US-20200106028-A1 | IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2020-04-02 | — | — | US | disclosed |
| US-10556898-B2 | Indazolyl-1,2,4-thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease | LYCERA CORPORATION (US) | 2020-02-11 | — | — | US | disclosed |
| US-20190276447-A1 | INDAZOLYL-1,2,4-THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE | LYCERA CORPORATION | 2019-09-12 | — | — | US | disclosed |
| US-20170362201-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
| US-9815818-B2 | Cot modulators and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170008873-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| US-20160380214-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2016-12-29 | — | — | US | disclosed |
| US-20150311455-A1 | Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device | UDC IRELAND LTD (IE) | 2015-10-29 | — | — | US | disclosed |
| US-9062084-B2 | Method of forming metal complex compound, and organic electroluminescence device | UDC Ireland (IE) | 2015-06-23 | — | — | US | disclosed |
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7449465-B2 | Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-11 | — | — | US | disclosed |
| US-20070203189-A1 | 2-Amino-4,5-Trisubstituted Thiazolyl Derivatives | LOVE CHRISTOPHER J | 2007-08-30 | — | — | US | disclosed |
| US-20070203189-A1 | 2-Amino-4,5-Trisubstituted Thiazolyl Derivatives | LOVE CHRISTOPHER J | 2007-08-30 | — | — | US | disclosed |
| US-7232838-B2 | 2-amino-4,5-trisubstituted thiazolyl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-19 | — | — | US | disclosed |
| US-7232838-B2 | 2-amino-4,5-trisubstituted thiazolyl derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-19 | — | — | US | disclosed |
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| US-20070129364-A1 | Pyrrolopyridine kinase inhibiting compounds | OSI PHARMACEUTICALS, INC. | 2007-06-07 | — | — | US | disclosed |
| US-20070129364-A1 | Pyrrolopyridine kinase inhibiting compounds | OSI PHARMACEUTICALS, INC. | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362201-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | TGFBR1 4432/4885TGFBR2 3991/4885NMT1 1324/4885 |
| US-20160380214-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | L1CAM, AP1M1, L3MBTL1 | TGFBR1 681/4885TGFBR2 1410/4885NMT1 1108/4885 |
| US-20190276447-A1 | INDAZOLYL-1,2,4-THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE | ROCK1, ROCK2, TNK2 | TGFBR1 1046/4885TGFBR2 1143/4885NMT1 3661/4885 |
| US-20150311455-A1 | Method Of Forming Metal Complex Compound, And Organic Electroluminescence Device | ZFR, PORCN, OR10J3 | TGFBR1 4322/4885TGFBR2 4244/4885NMT1 1755/4885 |
| US-20200106028-A1 | IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LAGE3, OXA1L, OPA1 | TGFBR1 2647/4885TGFBR2 4202/4885NMT1 2088/4885 |
| US-20070203189-A1 | 2-Amino-4,5-Trisubstituted Thiazolyl Derivatives | IFNG, IL15, IL5 | TGFBR1 65/4885TGFBR2 84/4885NMT1 1102/4885 |
| US-20070129364-A1 | Pyrrolopyridine kinase inhibiting compounds | BMX, ERBB2, FRK | TGFBR1 1091/4885TGFBR2 696/4885NMT1 4710/4885 |
| US-10556898-B2 | Indazolyl-1,2,4-thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease | ROCK1, ROCK2, TNK2 | TGFBR1 1046/4885TGFBR2 1143/4885NMT1 3661/4885 |
| US-20170008873-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | TGFBR1 4432/4885TGFBR2 3991/4885NMT1 1324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.