SCHEMBL127663

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9644828	0.93	FAAH (0.45)	TSHRTP53SOAT1KMT2AMEN1
	SCHEMBL24169230	0.88	—	—
	SCHEMBL3068716	0.87	TSHR (0.44)	TSHRTP53SOAT1KMT2AMEN1
	SCHEMBL28152979	0.86	CES2 (0.55)	TSHRTP53SOAT1KMT2AMEN1
	SCHEMBL11862251	0.84	FAAH (0.45)	TSHRTP53SOAT1KMT2AMEN1
	SCHEMBL9883960	0.83	—	—
	SCHEMBL8464759	0.82	FAAH (0.59)	TSHRTP53SOAT1KMT2AMEN1
	SCHEMBL9860515	0.82	FAAH (0.59)	TSHRTP53SOAT1KMT2AMEN1
	SCHEMBL14166874	0.82	FAAH (0.59)	TSHRTP53SOAT1KMT2AMEN1
	SCHEMBL7747844	0.82	FAAH (0.59)	TSHRTP53SOAT1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.