SCHEMBL1276808

SCHEMBL1276808

Oc1ccccc1[B-](c1c(F)c(F)c(F)c(F)c1F)(c1c(F)c(F)c(F)c(F)c1F)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALOX15 P16050 2/20 0.38
KDM4E B2RXH2 2/20 0.38
NPC1 O15118 2/20 0.38
CA2 P00918 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
CA4 P22748 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
EGFR P00533 1/20 0.38
FYN P06241 1/20 0.38
POLB P06746 1/20 0.38
CA3 P07451 1/20 0.38
CYP3A4 P08684 1/20 0.38
MMP9 P14780 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276645 0.96 ALDH1A1 (0.38) ALDH1A1HPGDHSD17B10ALOX15KDM4E
Butylamine SCHEMBL6909167 0.82 TSHR (0.31) TSHR
SCHEMBL29661112 0.79 MEN1 (0.33) ALDH1A1ALOX15MAPTCYP3A4TDP1
SCHEMBL5872296 0.78 MEN1 (0.33) ALDH1A1ALOX15MAPTCYP3A4TDP1
Dymanthine SCHEMBL1276492 0.78 DNM1 (0.40) ALDH1A1ALOX15MAPTCYP3A4TDP1
SCHEMBL1276666 0.78 MEN1 (0.35) ALDH1A1ALOX15MAPTCYP3A4TDP1
SCHEMBL5653811 0.78 MEN1 (0.33) ALDH1A1ALOX15MAPTCYP3A4TDP1
SCHEMBL5656345 0.78 MEN1 (0.33) ALDH1A1ALOX15MAPTCYP3A4TDP1
SCHEMBL5909814 0.72 ALDH1A1 (0.39) ALDH1A1HPGDHSD17B10ALOX15NPC1
SCHEMBL1276100 0.70 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10ALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299405-B1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2009-05-13 EP claimed
US-6800701-B2 USING COORDINATION CATALYSTS DOW GLOBAL TECHNOLOGIES INC. 2004-10-05 US claimed
US-20030216529-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2003-11-20 US claimed
EP-1299405-A1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-04-09 EP claimed
US-20020062011-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process DOW GLOBAL TECHNOLOGIES LLC 2002-05-23 US claimed
WO-2002002577-A1 POLYCYCLIC, FUSED RING COMPOUNDS, METAL COMPLEXES AND POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGY INC. (US) 2002-01-10 WO claimed
WO-2023191080-A1 POLYETHYLENE POWDER AND METHOD FOR PRODUCING SAME, AND OLEFIN POLYMERIZATION CATALYST AND METHOD FOR PRODUCING SAME 旭化成株式会社 2023-10-05 WO disclosed
WO-2023054514-A1 ULTRAHIGH-MOLECULAR-WEIGHT POLYETHYLENE POWDER AND SHAPED OBJECT OBTAINED BY SHAPING SAME 旭化成株式会社 2023-04-06 WO disclosed
US-10246566-B2 Polyethylene polymer powder and method of producing same ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-04-02 US disclosed
US-20180273708-A1 POLYETHYLENE POLYMER POWDER AND METHOD OF PRODUCING SAME ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-09-27 US disclosed
US-9469701-B2 Polyethylene powder ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-10-18 US disclosed
EP-2021382-B1 SUPPORTED ANTISTATIC POLYMERIZATION CATALYST NOVA CHEM INT SA (CH) 2016-08-17 EP disclosed
US-9362539-B2 Polyethylene powder, microporous membrane, and fiber ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-06-07 US disclosed
WO-1999028353-A1 OLEFIN POLYMERIZATION CATALYST AND METHOD FOR POLYMERIZING AN OLEFIN USING THE CATALYST ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-06-10 WO disclosed
EP-0898586-A1 PROCESS FOR PREPARING COPOLYMERS AND BLEND COMPOSITIONS CONTAINING THE SAME THE DOW CHEMICAL COMPANY (US) 1999-03-03 EP disclosed
US-5834393-A FOR POLYMERIZATION OF ALPHA OLEFINS THE DOW CHEMICAL COMPANY (US) 1998-11-10 US disclosed
WO-1998045337-A1 CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1998-10-15 WO disclosed
US-5783512-A Catalyst component dispersion comprising an ionic compound and solid addition polymerization catalysts containing the same THE DOW CHEMICAL COMPANY (US) 1998-07-21 US disclosed
WO-1998027119-A1 CATALYST COMPONENT DISPERSION COMPRISING AN IONIC COMPOUND AND SOLID ADDITION POLYMERIZATION CATALYSTS CONTAINING THE SAME THE DOW CHEMICAL COMPANY (US) 1998-06-25 WO disclosed
WO-1997043323-A1 PROCESS FOR PREPARING COPOLYMERS AND BLEND COMPOSITIONS CONTAINING THE SAME THE DOW CHEMICAL COMPANY (US) 1997-11-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216529-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process PIN1, ZC3H18, ORC3 ALDH1A1 3449/4885HPGD 2294/4885HSD17B10 2858/4885
US-20020062011-A1 Polycyclic, fused ring compounds, metal complexes and polymerization process PIN1, ZC3H18, ORC3 ALDH1A1 3449/4885HPGD 2294/4885HSD17B10 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.