Adenosine Triphosphate

Adenosine Triphosphate

SCHEMBL12789528

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)[C@@H]1O

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 7/20 0.94
P2RX1 P51575 4/20 0.94
P2RX3 P56373 4/20 0.94
P2RY2 P41231 3/20 0.94
P2RX2 Q9UBL9 2/20 0.94
SRC P12931 2/20 0.94
SMN1; SMN2 Q16637 2/20 0.94
ALDH1A1 P00352 2/20 0.94
P2RX4 Q99571 1/20 0.94
RNASEL Q05823 1/20 0.88
TRPM2 O94759 2/20 0.88
MACROD2 A1Z1Q3 1/20 0.88
SIRT6 Q8N6T7 1/20 0.88
MACROD1 Q9BQ69 1/20 0.88
TAS1R3 Q7RTX0 2/20 0.83
TAS1R1 Q7RTX1 2/20 0.83
DNPH1 O43598 1/20 0.83
PRKAB2 O43741 1/20 0.83
LDHA P00338 1/20 0.83
ADRB2 P07550 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9171542 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
SCHEMBL376008 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL8979 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL6242713 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL18784961 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL13722152 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL13722139 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL2227081 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL20550531 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2
Adenosine Triphosphate SCHEMBL8980 1.00 P2RY1 (0.94) P2RY1P2RX1P2RX3P2RY2P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240170-A1 POLYANIONIC ACIDS TO IMPROVE RECOVERY AND MINIMIZE SYSTEM LOSS WATERS TECHNOLOGIES CORPORATION (US) 2024-07-18 US disclosed
US-11912983-B2 Polyanionic acids to improve recovery and minimize system loss WATERS TECHNOLOGIES CORPORATION (US) 2024-02-27 US disclosed
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) EAGLE BIOLOGICS, INC. (US) 2023-11-21 US disclosed
US-20180153997-A1 Liquid Protein Formulations Containing Organophosphates EAGLE BIOLOGICS, INC. 2018-06-07 US disclosed
US-9913905-B2 Liquid pharmaceutical formulations for injection comprising thiamine pyrophosphate 1-(3-aminopropyl)-2-methyl-1H-imidazole and uses thereof EAGLE BIOLOGICS, INC. (US) 2018-03-13 US disclosed
US-20170363613-A1 SIMULTANEOUS DETECTION OF CANNIBALISM AND SENESCENCE AS PROGNOSTIC MARKER FOR CANCER INSTITUT GUSTAVE-ROUSSY (FR) 2017-12-21 US disclosed
US-9726661-B2 Simultaneous detection of cannibalism and senescence as prognostic marker for cancer INSTITUT GUSTAVE-ROUSSY (FR) 2017-08-08 US disclosed
WO-2017123072-A1 NEW POLYPHOSPHATE-DEPENDENT GLUCOKINASE AND METHOD FOR PRODUCING GLUCOSE 6-PHOSPHATE USING SAME 씨제이제일제당(주) 2017-07-20 WO disclosed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US disclosed
US-20160354491-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2016-12-08 US disclosed
US-20150185202-A1 SIMULTANEOUS DETECTION OF CANNIBALISM AND SENESCENCE AS PROGNOSTIC MARKER FOR CANCER INSTITUT GUSTAVE-ROUSSY (FR) 2015-07-02 US disclosed
US-9006208-B2 Agent for treatment of dry eye characterized by combining P2Y2 receptor agonist and hyaluronic acid or salt thereof, method for treating dry eye, and use of the P2Y2 receptor agonist and hyaluronic acid or salt thereof SANTEN PHARMACEUTICAL CO., LTD. (JP) 2015-04-14 US disclosed
US-9006208-B2 Agent for treatment of dry eye characterized by combining P2Y2 receptor agonist and hyaluronic acid or salt thereof, method for treating dry eye, and use of the P2Y2 receptor agonist and hyaluronic acid or salt thereof SANTEN PHARMACEUTICAL CO., LTD. (JP) 2015-04-14 US disclosed
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES EAGLE BIOLOGICS, INC. 2015-03-12 US disclosed
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES EAGLE BIOLOGICS, INC. 2015-03-12 US disclosed
US-20140072559-A1 Highly concentrated aqueous protein solution with reduced viscosity ADOCIA (FR) 2014-03-13 US disclosed
EP-2250247-B1 COMPOSITION RECKITT BENCKISER NV (NL) 2014-03-12 EP disclosed
US-20130172287-A1 AGENT FOR TREATMENT OF DRY EYE CHARACTERIZED BY COMBINING P2Y2 RECEPTOR AGONIST AND HYALURONIC ACID OR SALT THEREOF, METHOD FOR TREATING DRY EYE, AND USE OF THE P2Y2 RECEPTOR AGONIST AND HYALURONIC ACID OR SALT THEREOF SANTEN PHARMACEUTICAL CO., LTD. (JP) 2013-07-04 US disclosed
US-20110053819-A1 Composition RECKITT BENCKISER FINISH B.V. (NL) 2011-03-03 US disclosed
US-7569558-B2 Topical delivery of trace metals for skin care BIODERM RESEARCH (US) 2009-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140072559-A1 Highly concentrated aqueous protein solution with reduced viscosity DCTD, RNGTT, HNRNPUL2 P2RY1 3278/4885P2RX1 4148/4885P2RX3 4412/4885
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) PDE7A, PDE8A, PDE8B P2RY1 82/4885P2RX1 155/4885P2RX3 172/4885
US-20160354491-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 P2RY1 2661/4885P2RX1 3638/4885P2RX3 3314/4885
US-20150071921-A1 LIQUID PROTEIN FORMULATIONS CONTAINING ORGANOPHOSPHATES IGFBP1, IGFBP5, IGF2BP1 P2RY1 2607/4885P2RX1 2735/4885P2RX3 2600/4885
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 P2RY1 947/4885P2RX1 627/4885P2RX3 490/4885
US-20130172287-A1 AGENT FOR TREATMENT OF DRY EYE CHARACTERIZED BY COMBINING P2Y2 RECEPTOR AGONIST AND HYALURONIC ACID OR SALT THEREOF, METHOD FOR TREATING DRY EYE, AND USE OF THE P2Y2 RECEPTOR AGONIST AND HYALURONIC ACID OR SALT THEREOF P2RY2, P2RY12, P2RY13 P2RY1 5/4885P2RX1 20/4885P2RX3 32/4885
US-20180153997-A1 Liquid Protein Formulations Containing Organophosphates IGFBP1, IGFBP5, IGF2BP1 P2RY1 2607/4885P2RX1 2735/4885P2RX3 2600/4885
US-20110053819-A1 Composition POLI, CPSF7, CPSF6 P2RY1 872/4885P2RX1 1523/4885P2RX3 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.