Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129439 | 0.79 | MLYCD (0.35) | — | |
| SCHEMBL18071029 | 0.73 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL31078390 | 0.73 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL25165495 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL13574810 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| Lithium Ion SCHEMBL21963191 | 0.67 | — | — | |
| SCHEMBL9568936 | 0.67 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL12028940 | 0.67 | CDK2 (0.40) | ALDH1A1 | |
| SCHEMBL13563819 | 0.67 | EGLN2 (0.31) | ALDH1A1 | |
| SCHEMBL12620049 | 0.67 | EGLN2 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | disclosed |
| CN-116059203-A | Autotaxin inhibitors and uses thereof | 赛博治疗有限责任公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-4026549-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | Sabre Therapeutics LLC (US) | 2022-07-13 | — | — | EP | disclosed |
| US-20200215034-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | INSOLVENCY SERVICES GROUP, INC. | 2020-07-09 | — | — | US | disclosed |
| US-10632104-B2 | Autotaxin inhibitors and uses thereof | SABRE THERAPEUTICS LLC (US) | 2020-04-28 | — | — | US | disclosed |
| US-20180162859-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ATXCO, INC. | 2018-06-14 | — | — | US | disclosed |
| US-20180147185-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-05-31 | — | — | US | disclosed |
| EP-3302490-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | Pharmakea, Inc. (US) | 2018-04-11 | — | — | EP | disclosed |
| US-9926318-B2 | Tetracyclic autotaxin inhibitors | PHARMAKEA, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| WO-2016191427-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2016-12-01 | — | — | WO | disclosed |
| EP-3071569-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | Pharmakea Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| US-20160264575-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | DF 2024 IP ACQUISITION, LLC | 2016-09-15 | — | — | US | disclosed |
| WO-2015077502-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | PHARMAKEA, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-5395845-A | Insecticides | ROUSSEL-UCLAF (FR) | 1995-03-07 | — | — | US | disclosed |
| CN-1081675-A | By the new pyrethroid of thiazolic alcohol derivative, its preparation method and as the purposes of agricultural chemicals | ROUSSEL UCLAF (FR) | 1994-02-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147185-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SERPINB1, RNASE1 | ALDH1A1 4716/4885 |
| US-20180162859-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ENPP2, SERPINB1, UACA | ALDH1A1 4813/4885 |
| US-10632104-B2 | Autotaxin inhibitors and uses thereof | ENPP2, SERPINB1, RNASE1 | ALDH1A1 4716/4885 |
| US-20200215034-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SERPINB1, RNASE1 | ALDH1A1 4716/4885 |
| US-20160264575-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ENPP2, SERPINB1, UACA | ALDH1A1 4813/4885 |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | CBR3, CBR1, CYC1 | ALDH1A1 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.