Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | HTR1A | P08908 | 2/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | HTR3A | P46098 | 1/20 | 0.75 |
| ▸ | BACE1 | P56817 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311979 | 0.89 | TAAR1 (0.67) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| SCHEMBL12804316 | 0.87 | ESR1 (0.70) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL134515 | 0.87 | TAAR1 (1.00) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL4111 | 0.87 | TAAR1 (1.00) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL30831107 | 0.87 | TAAR1 (1.00) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL30831130 | 0.87 | TAAR1 (1.00) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL1804993 | 0.84 | TAAR1 (0.95) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL7742928 | 0.84 | TAAR1 (0.95) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL2574990 | 0.84 | TAAR1 (0.95) | TAAR1KDM4EALDH1A1HTR1AADRA2A | |
| Tyramine SCHEMBL2121 | 0.84 | TDP1 (1.00) | TAAR1KDM4EALDH1A1HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4733383-A1 | CULTURE MEDIUM AND BLOOD CELL CLONE, AND METHOD FOR PRODUCING SAME | Japan Institute for Health Security (JP) | 2026-04-29 | — | — | EP | claimed |
| WO-2024262610-A1 | CULTURE MEDIUM AND BLOOD CELL CLONE, AND METHOD FOR PRODUCING SAME | 国立研究開発法人国立国際医療研究センター | 2024-12-26 | — | — | WO | claimed |
| US-20240101963-A1 | SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2024-03-28 | — | — | US | claimed |
| EP-4271399-A1 | ENHANCED DIFFERENTIATION OF BETA CELLS | Vertex Pharmaceuticals Incorporated (US) | 2023-11-08 | — | — | EP | claimed |
| US-20220265775-A1 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION | UNIV MINNESOTA (US) | 2022-08-25 | — | — | US | claimed |
| WO-2022147056-A1 | ENHANCED DIFFERENTIATION OF BETA CELLS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-07-07 | — | — | WO | claimed |
| US-20210113120-A1 | Vaginal Measurements Using a Vaginal Ring | LIGALLI B.V. (NL) | 2021-04-22 | — | — | US | claimed |
| EP-3773199-A1 | VAGINAL MEASUREMENTS USING A VAGINAL RING | Ligalli B.V. (NL) | 2021-02-17 | — | — | EP | claimed |
| WO-2021021927-A1 | COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-02-04 | — | — | WO | claimed |
| WO-2019197486-A1 | VAGINAL MEASUREMENTS USING A VAGINAL RING | LIGALLI B.V. (NL) | 2019-10-17 | — | — | WO | claimed |
| US-7321065-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-01-22 | — | — | US | claimed |
| WO-2007059039-A1 | THYROXINE DERIVATIVES FOR PRECONDITIONING AGAINST STROKE | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2007-05-24 | — | — | WO | claimed |
| EP-1625111-A4 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2007-04-25 | — | — | EP | claimed |
| US-20060035980-A1 | Thyronamine derivatives and analogs and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-16 | — | — | US | claimed |
| EP-1625111-A2 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-02-15 | — | — | EP | claimed |
| US-6979750-B1 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-27 | — | — | US | claimed |
| US-20050267207-A1 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-12-01 | — | — | US | claimed |
| US-20050096485-A1 | Thyronamine derivatives and analogs and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-05-05 | — | — | US | claimed |
| WO-2004093800-A2 | THYRONAMINE DERIVATIVES AND ANALOGS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-11-04 | — | — | WO | claimed |
| CN-1518469-A | Dermatological preparations | �����ɷ� | 2004-08-04 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035980-A1 | Thyronamine derivatives and analogs and methods of use thereof | TPO, TSHR, THRB | TAAR1 152/4885KDM4E 3632/4885ALDH1A1 2148/4885 |
| US-20050096485-A1 | Thyronamine derivatives and analogs and methods of use thereof | TPO, TSHR, THRB | TAAR1 198/4885KDM4E 3754/4885ALDH1A1 2156/4885 |
| US-20240101963-A1 | SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME | IAPP, ALPG, PNLIP | TAAR1 4310/4885KDM4E 4115/4885ALDH1A1 3569/4885 |
| US-20050267207-A1 | Thyronamine derivatives and analogs and methods of use thereof | TPO, TSHR, THRB | TAAR1 152/4885KDM4E 3632/4885ALDH1A1 2148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.