SCHEMBL20672211

SCHEMBL20672211

Oc1ccc(CCOCCc2ccc(Oc3ccc(O)cc3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 2/20 0.58
▸ ESR2 Q92731 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ LTA4H P09960 7/20 0.50
▸ CALM1 P0DP23 1/20 0.50
▸ NR1H2 P55055 1/20 0.50
▸ BAX Q07812 1/20 0.50
▸ CA2 P00918 1/20 0.46
▸ NPC1 O15118 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ HTR1A P08908 1/20 0.45
▸ ADRA2A P08913 1/20 0.45
▸ SLC6A2 P23975 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ HTR3A P46098 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8389404 0.89 ESR1 (0.65) ESR1ESR2KMT2ALTA4HCALM1
SCHEMBL12804316 0.87 ESR1 (0.70) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL28001756 0.84 APP (0.61) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL9358826 0.81 CA2 (0.60) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL10527969 0.80 ESR1 (0.59) ESR1ESR2KMT2ALTA4HCALM1
SCHEMBL8939444 0.80 ESR1 (0.60) ESR1ESR2KMT2AMEN1LTA4H
Thyronamine SCHEMBL449823 0.79 TAAR1 (0.75) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL28928030 0.79 ALDH1A1 (0.58) KMT2AMEN1NPC1MAPTRAB9A
SCHEMBL6062245 0.79 LTA4H (0.68) ESR1ESR2KMT2AMEN1LTA4H
SCHEMBL8914902 0.79 ESR1 (0.53) ESR1ESR2KMT2ALTA4HCALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030983-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-07-09 — — US disclosed
US-20230167238-A1 POLYMETRIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-06-01 — — US disclosed
US-11649203-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-05-16 — — US disclosed
US-20220002478-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2022-01-06 — — US disclosed
US-11124603-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-09-21 — — US disclosed
US-20200369597-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-11-26 — — US disclosed
US-10774030-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-09-15 — — US disclosed
US-20200181321-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2020-06-11 — — US disclosed
US-20190023644-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-01-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181321-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, MYB ESR1 400/4885ESR2 2422/4885KMT2A 4135/4885
US-12030983-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, MYB ESR1 346/4885ESR2 2377/4885KMT2A 4048/4885
US-11124603-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, MYB ESR1 400/4885ESR2 2422/4885KMT2A 4135/4885
US-20190023644-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, HPD ESR1 1832/4885ESR2 3306/4885KMT2A 3844/4885
US-20220002478-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, MYB ESR1 346/4885ESR2 2377/4885KMT2A 4048/4885
US-10774030-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, HPD ESR1 1565/4885ESR2 3157/4885KMT2A 3778/4885
US-20200369597-A1 POLYMERIC BIOMATERIALS DERIVED FROM PHENOLIC MONOMERS AND THEIR MEDICAL USES TH, TYR, TYRO3 ESR1 1387/4885ESR2 2734/4885KMT2A 4271/4885
US-11649203-B2 Polymeric biomaterials derived from phenolic monomers and their medical uses TH, TYR, TYRO3 ESR1 1387/4885ESR2 2734/4885KMT2A 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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