Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647692 | 0.83 | PGR (0.41) | PGRALDH1A1MAPTHPGDMARK3 | |
| SCHEMBL12647693 | 0.74 | KDM4E (0.43) | ALDH1A1MAPTHPGDNPSR1GAA | |
| SCHEMBL12809947 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL1408900 | 0.69 | MAPT (0.39) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL12809942 | 0.68 | ACACA (0.39) | ALDH1A1MAPTHPGDNPSR1GAA | |
| SCHEMBL10948887 | 0.66 | ELANE (0.63) | PGRALDH1A1GAAMARK3 | |
| SCHEMBL1408738 | 0.66 | MEN1 (0.39) | ALDH1A1MAPTNPSR1LMNAMEN1 | |
| SCHEMBL11654508 | 0.63 | PGR (0.58) | PGRALDH1A1GAAMARK3 | |
| SCHEMBL6370043 | 0.63 | GPR84 (0.58) | ALDH1A1MAPTHPGDNPSR1LMNA | |
| SCHEMBL11747305 | 0.62 | ALDH1A1 (0.62) | ALDH1A1POLBMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034221-B1 | DIBENZORHODAMINE DYES USEFUL AS FLUORESCENT LABELLING AGENTS | LIFE TECHNOLOGIES CORP (US) | 2014-05-14 | — | — | EP | disclosed |
| EP-2295503-A1 | Dibenzorhodamine dyes useful as fluorescent labelling agents | Applera Corporation (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2186801-A2 | Intermediates for synthesizing dibenzorhodamine dyes | Applera Corporation (US) | 2010-05-19 | — | — | EP | disclosed |
| US-20070099210-A1 | Methods of Labelling Polynucleotides with Dibenzorhodamine Dyes | APPLERA CORPORATION (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099210-A1 | Methods of Labelling Polynucleotides with Dibenzorhodamine Dyes | NUDT1, DUT, NSUN3 | PGR 2933/4885ALDH1A1 1645/4885POLB 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.