Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | EPM2A | O95278 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 6/20 | 0.36 |
| ▸ | GABRD | O14764 | 6/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.36 |
| ▸ | GABRE | P78334 | 6/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14039182 | 0.93 | PIM1 (0.40) | PIM1EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL12811607 | 0.83 | EPM2A (0.50) | PIM1EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL1637246 | 0.83 | PIM1 (0.52) | PIM1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21622835 | 0.80 | NPC1 (0.42) | PIM1EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL12811248 | 0.79 | PIM1 (0.40) | PIM1EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL216673 | 0.79 | EPM2A (0.53) | PIM1EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL29432245 | 0.79 | EPM2A (0.53) | PIM1EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL10227300 | 0.77 | EPM2A (0.49) | PIM1EPM2APTPN2PTPN1PTPN22 | |
| SCHEMBL10227215 | 0.77 | PIM1 (0.50) | PIM1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL25989887 | 0.76 | GPR3 (0.38) | EPM2APTPN2PTPN1PTPN22GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| US-8318323-B2 | Polycyclic compounds and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8318323-B2 | Polycyclic compounds and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| EP-2301921-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130020563-A1 | POLYCYCLIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | KCNC1, EED, BMI1 | PIM1 1149/4885EPM2A 1912/4885PTPN2 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.