Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813371 | 0.83 | CETP (0.35) | HSD11B1PDE2ATOP2ATOP2B | |
| SCHEMBL16498935 | 0.82 | PDE2A (0.45) | PDE2A | |
| SCHEMBL12813191 | 0.81 | KMT2A (0.33) | SLC6A2HSD11B1ALDH1A1 | |
| SCHEMBL12813364 | 0.81 | ALDH1A1 (0.34) | SLC6A3ALDH1A1 | |
| SCHEMBL12813412 | 0.79 | SLC6A2 (0.35) | SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL12813156 | 0.79 | HPGD (0.35) | — | |
| SCHEMBL12813348 | 0.78 | RXRA (0.38) | — | |
| SCHEMBL12813382 | 0.75 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL16499157 | 0.75 | RARB (0.34) | HSD11B1ALDH1A1TOP2ATOP2B | |
| SCHEMBL12813698 | 0.74 | RXRA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |