Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 4/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813339 | 0.88 | RARB (0.42) | TAS1R3TAS1R1TAS1R2RARBKMT2A | |
| SCHEMBL12813534 | 0.87 | MEN1 (0.41) | RARBPOLBKMT2AMEN1RARA | |
| SCHEMBL12813381 | 0.84 | RARB (0.41) | RARBRARARARGRXRA | |
| SCHEMBL12813449 | 0.81 | RARB (0.41) | RARBSMN1; SMN2ALDH1A1RARARARG | |
| SCHEMBL12813035 | 0.80 | HTT (0.49) | TAS1R3TAS1R1RARBKMT2AMEN1 | |
| SCHEMBL12813501 | 0.80 | HTT (0.45) | RARBSMN1; SMN2POLBALDH1A1RARA | |
| SCHEMBL12813470 | 0.80 | RARB (0.38) | RARBSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL16499391 | 0.79 | RARB (0.40) | RARBRARARARGRXRA | |
| SCHEMBL12813347 | 0.78 | ALDH1A1 (0.47) | RARBSMN1; SMN2ALDH1A1RARARARG | |
| SCHEMBL16499346 | 0.77 | EPHX2 (0.40) | RARBRARARARGRXRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012134971-A2 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |