Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | PDE2A | O00408 | 5/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813035 | 0.87 | HTT (0.49) | RARBLMNAMAPK1HTTRAB9A | |
| SCHEMBL12813339 | 0.83 | RARB (0.42) | RARBRXRARARARARG | |
| SCHEMBL12813157 | 0.82 | NPC1 (0.40) | EPHX2RARBRAB9A | |
| SCHEMBL12813470 | 0.78 | RARB (0.38) | RARBLMNAMAPK1RXRARARA | |
| SCHEMBL12813462 | 0.77 | ALOX15 (0.44) | RARBLMNAHTTRXRARARA | |
| SCHEMBL12813736 | 0.77 | TAS1R3 (0.40) | RARBLMNAHTTRAB9ARXRA | |
| SCHEMBL16499391 | 0.77 | RARB (0.40) | RARBRXRARARARARG | |
| SCHEMBL12813449 | 0.76 | RARB (0.41) | RARBLMNAMAPK1RAB9ARXRA | |
| SCHEMBL12813472 | 0.75 | SRD5A2 (0.44) | EPHX2RARBRXRARARARARG | |
| SCHEMBL12813501 | 0.75 | HTT (0.45) | RARBLMNAHTTRXRARARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011155983-A1 | OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE | BIKAM PHARMACEUTICALS INC. (US) | 2011-12-15 | — | — | WO | disclosed |