Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | CPT1A | P50416 | 2/20 | 0.34 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12817890 | 0.89 | HSPD1 (0.40) | GCKCPT2CPT1ACPT1BGAA | |
| SCHEMBL12819156 | 0.87 | PGR (0.39) | GCKCPT2CPT1ACPT1BGAA | |
| SCHEMBL12817711 | 0.85 | GCK (0.36) | GCKCPT2CPT1ACPT1BGAA | |
| SCHEMBL12817769 | 0.85 | CYP2C9 (0.38) | GCKCPT1ACPT1BGAAL3MBTL1 | |
| SCHEMBL12817702 | 0.82 | PKM (0.41) | CPT2CPT1ACPT1BALDH1A1MAPT | |
| SCHEMBL12818327 | 0.82 | CYP11B1 (0.38) | CPT2CPT1ACPT1BCNR1CNR2 | |
| SCHEMBL12817644 | 0.80 | PGR (0.37) | GCKCPT2CPT1ACPT1BCNR1 | |
| SCHEMBL12818293 | 0.80 | CPT2 (0.35) | GCKCPT2CPT1ACPT1BGAA | |
| SCHEMBL12817768 | 0.80 | BRD4 (0.40) | CPT2CPT1ACPT1BCNR1CNR2 | |
| SCHEMBL1818508 | 0.79 | CNR1 (0.39) | CPT2CPT1ACPT1BCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | disclosed |