Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 2/20 | 0.35 |
| ▸ | CPT1A | P50416 | 2/20 | 0.35 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12817618 | 0.83 | MEN1 (0.41) | CPT1ACPT1BGCKCYP3A4CYP2D6 | |
| SCHEMBL12818569 | 0.83 | PKM (0.42) | CPT2CPT1ACPT1BALDH1A1MAPT | |
| SCHEMBL12817890 | 0.82 | HSPD1 (0.40) | CPT2CPT1ACPT1BGCKCNR1 | |
| SCHEMBL12817768 | 0.81 | BRD4 (0.40) | CPT2CPT1ACPT1BCNR1CNR2 | |
| SCHEMBL12817711 | 0.80 | GCK (0.36) | CPT2CPT1ACPT1BGCKOGA | |
| SCHEMBL12818060 | 0.80 | KDM2B (0.39) | CPT2CPT1ACPT1BCNR1CNR2 | |
| SCHEMBL12818272 | 0.80 | GCK (0.35) | CPT2CPT1ACPT1BGCKOGA | |
| SCHEMBL12819156 | 0.80 | PGR (0.39) | CPT2CPT1ACPT1BGCKOGA | |
| SCHEMBL12817775 | 0.78 | GAA (0.40) | CPT2CPT1ACPT1BCNR1CNR2 | |
| SCHEMBL12818327 | 0.75 | CYP11B1 (0.38) | CPT2CPT1ACPT1BCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| WO-2012130306-A1 | BICYCLIC 2,3-DIHYRDOBENZAZINE COMPOUNDS FOR USE IN THERAPY | ELARA PHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | WO | disclosed |