Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987381 | 0.84 | BCHE (0.62) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL12821517 | 0.75 | PTGS2 (0.46) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL25055359 | 0.74 | MIF (0.74) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL30987377 | 0.74 | MIF (0.55) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL30987390 | 0.74 | MIF (0.55) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL30987383 | 0.73 | NPC1 (0.51) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL16473838 | 0.73 | NOTUM (0.48) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL3270459 | 0.72 | NOTUM (0.57) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL30987379 | 0.71 | NOTUM (0.50) | NOTUMALDH1A1CA12CA1CA2 | |
| SCHEMBL30987376 | 0.71 | CA2 (0.51) | NOTUMALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140107327-A1 | METHODS FOR PREPARING DEUTERATED 1,2,3-TRIAZOLES | RESEARCH FOUDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2014-04-17 | — | — | US | disclosed |
| WO-2012135112-A2 | METHODS FOR PREPARING DEUTERATED 1,2,3-TRIAZOLES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2012-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107327-A1 | METHODS FOR PREPARING DEUTERATED 1,2,3-TRIAZOLES | APOBEC3A, RAD23B, APOBEC3G | NOTUM 3413/4885ALDH1A1 682/4885CA12 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.