Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987381 | 0.88 | BCHE (0.62) | MIFNOTUMCA12CA1CA2 | |
| SCHEMBL30987376 | 0.86 | CA2 (0.51) | MIFNOTUMCA12CA1CA2 | |
| SCHEMBL25055359 | 0.86 | MIF (0.74) | MIFNOTUMCA12CA1CA2 | |
| SCHEMBL30987377 | 0.86 | MIF (0.55) | MIFNOTUMCA12CA1CA2 | |
| SCHEMBL30987393 | 0.85 | ABCG2 (0.57) | MIFNOTUMCA12CA1CA2 | |
| SCHEMBL28147063 | 0.82 | FLT3 (0.63) | MIFCA12CA1CA2CA9 | |
| SCHEMBL30987380 | 0.80 | NOTUM (0.52) | MIFNOTUMCA12CA1CA2 | |
| SCHEMBL29158504 | 0.79 | BCHE (0.51) | MIFCA12CA1CA2CA9 | |
| SCHEMBL3270459 | 0.79 | NOTUM (0.57) | MIFNOTUMCA12CA1CA2 | |
| SCHEMBL28645410 | 0.79 | BCHE (0.51) | MIFNOTUMCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |